austinday Lv 1
Hi Foldit!
Thanks for surviving my various biotin puzzles! I know some of the restrictions have made them very difficult. We've been experimenting with various puzzle setups and I think we'll soon find a happy intermediate between impossible and hard. :)
As for the results of the previous puzzles, I was pleasantly surprised with some of the solutions that were turned in. I'm curious to know whether any of you were able to find any strategies that seemed to work better than randomly searching. In future puzzles, I will include those solutions along with some others we have generated as the starting structures, with the primary goal being to maintain the hydrogen bonds while also pursuing the best packing score. We have a few more tweaks to apply, but be confident that I won't ask you all to do the impossible anymore. (find those bonds from scratch).