Problem with T-cell Lymphoma Invasion Protein physics?

[BootsMcGraw]

I've stumbled upon an odd development while working the T-cell Lymphoma Invasion Protein.

The loop between 9-Isoleucine and 15-Phenylalanine is acting strangely. At the end of a rebuild script, the highest scoring structure had this loop literally bent back upon itself (see figure1.png). When I tried to rebuild it manually, it stretched out to freakish proportions, and the score dropped to negative infinity. (Well, close enough.) I was too flabbergasted to get a screenshot.

When I did manage to get the loop back into a more reasonable shape, I shook the sidechains. 11-Lysine decided to then bury itself INSIDE the backbone (see figure2.png and figure3.png for before and after photos).

I call "BUG!" This protein ain't behavin'.

[BootsMcGraw]

Changing "Type" to "Bug".

[Rav3n_pl]

It looks to me like ci=0 rebuild resoult, not a bug…

[infjamc]

Actually, it's a feature rather than a bug :-)

According to the developers' official reply ( see http://fold.it/portal/node/989418 ), the abnormal backbone in the 9-15 loop was intentional because several residues were missing.

[beta_helix]

Thanks for pointing to that, infjamc… Closing feedback.

[Seth Cooper]

Marking as resolved.