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CSIRO scientists and collaborators have made major inroads in cracking a structure of the protein thought to cause Alzheimer’s disease.
Dr Varghese – who played a major role in the development of the current anti-influenza drugs – said the CSIRO team was the first to successfully crystallize the part of amyloid beta that forms plaque by fusing it to a shark antibody to prevent clumping.
A co-author of the paper, Professor Colin Masters from the Mental Health Research Institute at the University of Melbourne, said the structure of the amyloid beta has been sought for the past 25 years.
http://www.csiro.au/news/Alzheimers-diseases-research-inroads.html
