Foldit accuracy

Started by Brad Taylor

Brad Taylor Lv 1

So I have a general question about the tools underneath Foldit. When we find a max score using Foldit, how closely does would that that reflect the minimum energy state for a protein, and how closely would that reflect the native protein state?

I assume that there must be a lot of simplifications to even get this to function on a PC and I don't expect anything close to perfection from this amazing tool. I'd just like to get a better sense of where it is. Given that this is a competition, what are the chances the Foldit is accurate is enough to identify the native state?

veritas2 Lv 1

We're trying to figure out that question ourselves. We're comparing the foldit results with actual results in an attempt to get an actual RMSD value of sorts