SCI CHAT QUESTION THREAD (September 2016)

[alcor29]

The Nature communication was published online. Will it ever be published in hard copy?

[tokens]

I've noticed that the recent denovo puzzles look like they were designed in foldit (possibly by foldit players). Can you confirm this? Also can you comment on how the designs were chosen and on what you hope to learn from posting these puzzles?

[tokens]

I'm curious to get an answer to this forum post: http://fold.it/portal/node/2002580

[Bruno Kestemont]

Supplementary note 2: "this highly conserved channel is the most likely α - synuclein binding site".

α - synuclein is a Human protein.

Butler et al (2016), Dopamine Transporter Activity Is Modulated by α-Synuclein:

"α-Synuclein is implicated in neurodegenerative disease and drug addiction."

"Understanding the mechanisms associated with α-synuclein regulation of DAT may reveal disease-modifying targets for the treatment of pathologies associated with DA dysregulation."

Question:

YPL067C being a yeast protein, what do you expect with this discovery?
-could researchers then find similar Human HTCs that regulate DTA?
-is YPL067C a toxical and/or a potential drug?