Hey everyone,
We're about to push a big update to the developer preview soon with additions and changes to Foldit Small Molecule Design. You can read more about this exciting new mode here. Read below for a full list of the changes:
- A major overhaul and update to the Small Molecule Design tool.
- Two new tutorials demonstrating how to use Small Molecule Design.
- A new "Binding Site" option in the "View Protein" section of the View Options – this is like Cartoon Ligand, but hides parts of the protein which are far from the ligand.
- Updates to the underlying small molecule handling code.
- Updates to the Ligand Substructure objective.
Combination of overlaid h bond indicators and all orange in edit mode makes this difficult.
Sorry about that - this has to do with your view option settings. Some of the view options which are more tailored for protein folding and protein design don't work too well for ligand design puzzles.
We recommend you adjust your view options to Color: "Score/Hydro+CPK" and View Protein: "Binding Site" (or "Cartoon Ligand"). But feel free to play around with the view settings to come up with settings that you like best. (For those who aren't too familiar with the Selection Interface, you can get to the View Options dialog by clicking the green Foldit button in the lower left corner.)
We're looking into ways of adjusting the puzzle setting such that we can load recommended view options on puzzle load, but for now you'll have to tweak things manually.
Many thanks for the suggestion. It seems that during each edit the atoms types are also lost so the view settings need to be adjusted each time. This makes the editing process more difficult.
Is it possible to play the ligand design tutorials without first playing the protein folding tutorials? This would be useful in my opinion as a quicker entry into ligand design.
Three clicks to undo one edit if I see it correctly.
