Lab Report #26: Small Molecule Design

[bkoep]

Tackle a different kind of research challenge with new tools for designing small molecules in Foldit!

NEWS

• New tools for small molecule design

PUZZLE UPDATES

• Design PROTAC small molecules

DESIGN OF THE MONTH

• A symmetric D2 tetramer, designed by Skippysk8s</a>, Enzyme, and an anonymous teammate in Puzzle 2050. A fully-satisfied H-bond network helps to prevent off-target assembly. Take a look for yourself in the November Design of the Month sandbox puzzle.

[alcor29]

Thanks bkoep. This was very helpful to the understanding of what we need to do. There is one category however which I still don't understand and perhaps you can elucidate a bit: What constitutes and "undesirable group?"

[alcor29]

Amides etc.