Lab Report #32: Good Rotations

Started by bkoep

bkoep Staff Lv 1

Collaborators are now testing VHL ligand designs in the lab, and new software features put the focus on rotatable bonds to help us create more effective molecules.

NEWS

PUZZLE UPDATES

  • KLHDC2 ligand design

DESIGN OF THE MONTH

  • A CD47 binder design by alcor29 in Puzzle 2132. The binding interface features a balance of hydrophobics (for tight binding) and polar sidechains (for folding and BUNS satisfaction). See for yourself in the Design of the Month sandbox puzzle.