Upcoming Science Chat on July 18th

Started by smortier

Bruno Kestemont Lv 1

Ideal SS sheets are not straight.

However, working with initial straight sheets seem to give more points at the end.

And tweak too tends to straight the sheets.

Are ideal sheets straight or not ?

Susume Lv 1

Have there been any novel-shaped foldit designs (shapes not found in nature) that have performed well in Rosetta or in the lab?

Susume Lv 1

Baker lab has had some recent success in producing thousands of small protein designs computationally. Is there still a place for hand-crafted designs like foldit players produce?

spvincent Lv 1

If you were going to add an extra amino acid to the standard set of twenty,as now seems possible, what would it be?

smortier Lv 1

"can we understand why the ideal loop library is so limited that one can not do a true Rossmann 2 by 2 fold? It would need some "yellow" glycine direction loops from sheet to helix. I asked on the last big protein puzzle. I want to understand if such a fold is not "ideal" – seems odd to me as it occurs often in nature. I won't be on science chat, but ran my poor little machine into the ground trying one with 6 AA sheets and one with 8 AA sheets. I'd really like feedback"