Up the ligand-in-the-compound-library bonus to 10000

Started by Bletchley Park

Bletchley Park Lv 1

Please up the ligand bonus to 10000 for those that are in the compound list.
I find that fantasy structures can still be made and score high without being in the compound library.

rmoretti Staff Lv 1

@"Bletchley Park" The amount of the bonus is something we monitor and adjust over the course of a puzzle series based on the compounds we're seeing scoring highly. It's set (along with the other bonus values & thresholds) in consultation with the experimental collaborators of the project. While in many cases the collaborators want to focus on compound library compounds, often they're also potentially interested in compounds which aren't necessarily library compounds. Often there's compounds which aren't in the library but are still interesting. Not being in the library doesn't mean they're not "real" compounds, just that they're potentially harder to obtain/synthesize than library compounds. (And if they're relatively close to library compounds, they might not be all that more difficult to synthesize.)

So it's a balancing act, trying to increase the compound library bonus enough to focus exploration on easily-obtainable compounds, while not necessarily penalizing free exploration. Be assured we generally do monitor the results as they come in, and attempt to adjust the settings (including the compound library bonus) to promote the sorts of molecules we (or rather our experimental collaborators) are interested in.