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1012: Unsolved De-novo Freestyle

Closed since over 11 years ago

Intermediate Overall Prediction

Summary

Created
November 12, 2014
Expires
Max points
100
Description

We are giving you this unsolved vascular endothelial growth factor protein as a freestyle puzzle to start. We will post another round for this protein later, giving you server predictions as starting models, but we'd like you to just work with this extended chain for now (as homology-based methods have failed to solve this protein). More info in the puzzle comments, including a blogpost about this unsolved protein.

Top groups

  1. Avatar for Deleted group 11. Deleted group pts. 8,491
  2. Avatar for Russian team 12. Russian team 10 pts. 8,486
  3. Avatar for SETI.Germany 13. SETI.Germany 7 pts. 8,287
  4. Avatar for Deleted group 14. Deleted group pts. 8,277
  5. Avatar for Italiani Al Lavoro 15. Italiani Al Lavoro 4 pts. 8,034
  6. Avatar for DCC Folders 16. DCC Folders 3 pts. 7,975
  7. Avatar for Repro-men 17. Repro-men 2 pts. 7,886
  8. Avatar for Waverki 18. Waverki 2 pts. 7,858
  9. Avatar for Natural Abilities 19. Natural Abilities 1 pt. 7,787
  10. Avatar for USD_IMB_2014 20. USD_IMB_2014 1 pt. 7,724
  1. Avatar for Galaxie
    1. Galaxie Lv 1
    100 pts. 9,072
  2. Avatar for Threeoak 2. Threeoak Lv 1 90 pts. 9,058
  3. Avatar for gmn 3. gmn Lv 1 80 pts. 9,054
  4. Avatar for jamiexq 4. jamiexq Lv 1 71 pts. 9,050
  5. Avatar for alwen 5. alwen Lv 1 63 pts. 9,044
  6. Avatar for Vredeman 6. Vredeman Lv 1 55 pts. 9,043
  7. Avatar for Lindata 7. Lindata Lv 1 49 pts. 9,037
  8. Avatar for reefyrob 8. reefyrob Lv 1 43 pts. 9,031
  9. Avatar for LociOiling 9. LociOiling Lv 1 37 pts. 9,030
  10. Avatar for brgreening 10. brgreening Lv 1 32 pts. 9,024

Comments

beta_helix Staff Lv 1

The secondary structure predictions for this puzzle haven't come back from the SAM server yet, so these are the ones that were used for the starting chain:

The higher the number, the higher the confidence of the secondary structure prediction above it.

In this puzzle, the "High Wiggle Power" option has been disabled.

Please read the new blogpost about this protein.

beta_helix Staff Lv 1

The sequence logo predicted by the SAM server finally finished:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.