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1012: Unsolved De-novo Freestyle

Closed since over 11 years ago

Intermediate Overall Prediction

Summary

Created
November 12, 2014
Expires
Max points
100
Description

We are giving you this unsolved vascular endothelial growth factor protein as a freestyle puzzle to start. We will post another round for this protein later, giving you server predictions as starting models, but we'd like you to just work with this extended chain for now (as homology-based methods have failed to solve this protein). More info in the puzzle comments, including a blogpost about this unsolved protein.

Top groups

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  3. Avatar for SETI.Germany 13. SETI.Germany 7 pts. 8,287
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  7. Avatar for Repro-men 17. Repro-men 2 pts. 7,886
  8. Avatar for Waverki 18. Waverki 2 pts. 7,858
  9. Avatar for Natural Abilities 19. Natural Abilities 1 pt. 7,787
  10. Avatar for USD_IMB_2014 20. USD_IMB_2014 1 pt. 7,724
  1. Avatar for franse 231. franse Lv 1 1 pt. 707
  2. Avatar for Fishmann 232. Fishmann Lv 1 1 pt. 0
  3. Avatar for TOMINO2004 233. TOMINO2004 Lv 1 1 pt. 0
  4. Avatar for katanyag 234. katanyag Lv 1 1 pt. 0
  5. Avatar for deLaCeiba 235. deLaCeiba Lv 1 1 pt. 0
  6. Avatar for Neil M 236. Neil M Lv 1 1 pt. 0
  7. Avatar for sheerbliss 237. sheerbliss Lv 1 1 pt. 0
  8. Avatar for spvincent 238. spvincent Lv 1 1 pt. 0
  9. Avatar for qooloop 239. qooloop Lv 1 1 pt. 0
  10. Avatar for matosfran 240. matosfran Lv 1 1 pt. 0

Comments

beta_helix Staff Lv 1

The secondary structure predictions for this puzzle haven't come back from the SAM server yet, so these are the ones that were used for the starting chain:

The higher the number, the higher the confidence of the secondary structure prediction above it.

In this puzzle, the "High Wiggle Power" option has been disabled.

Please read the new blogpost about this protein.

beta_helix Staff Lv 1

The sequence logo predicted by the SAM server finally finished:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.