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1012: Unsolved De-novo Freestyle

Closed since over 11 years ago

Intermediate Overall Prediction

Summary


Created
November 12, 2014
Expires
Max points
100
Description

We are giving you this unsolved vascular endothelial growth factor protein as a freestyle puzzle to start. We will post another round for this protein later, giving you server predictions as starting models, but we'd like you to just work with this extended chain for now (as homology-based methods have failed to solve this protein). More info in the puzzle comments, including a blogpost about this unsolved protein.

Top groups


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  2. Avatar for Mojo Risin' 22. Mojo Risin' 1 pt. 7,536
  3. Avatar for It's over 9000! 23. It's over 9000! 1 pt. 7,311
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  1. Avatar for hatimbelg 151. hatimbelg Lv 1 2 pts. 7,270
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  3. Avatar for Cornpop 153. Cornpop Lv 1 1 pt. 7,263
  4. Avatar for mirjamvandelft 154. mirjamvandelft Lv 1 1 pt. 7,229
  5. Avatar for waverka2 155. waverka2 Lv 1 1 pt. 7,224
  6. Avatar for rinze 156. rinze Lv 1 1 pt. 7,153
  7. Avatar for martinf 157. martinf Lv 1 1 pt. 7,128
  8. Avatar for brokenbadguy 158. brokenbadguy Lv 1 1 pt. 7,108
  9. Avatar for Imeturoran 159. Imeturoran Lv 1 1 pt. 7,076
  10. Avatar for dahast.de 160. dahast.de Lv 1 1 pt. 7,057

Comments


beta_helix Staff Lv 1

The secondary structure predictions for this puzzle haven't come back from the SAM server yet, so these are the ones that were used for the starting chain:

The higher the number, the higher the confidence of the secondary structure prediction above it.

In this puzzle, the "High Wiggle Power" option has been disabled.

Please read the new blogpost about this protein.

beta_helix Staff Lv 1

The sequence logo predicted by the SAM server finally finished:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.