Placeholder image of a protein
Icon representing a puzzle

1028: Revisiting Electron Density Puzzle 730

Closed since over 11 years ago

Intermediate Overall Prediction Electron Density

Summary

Created
December 20, 2014
Expires
Max points
100
Description

We're revisiting this old electron density puzzle to test some recent changes to Foldit! In this puzzle, there are bits of density which don't belong to the copy of the protein that you're working on. You'll have to decide which bits of density to match with, and which bits to ignore. Try to fit the protein into the density to get the best score! Secondary structure predictions are posted in the puzzle comments along with info about available tools in the game.

Top groups

  1. Avatar for Waverki 21. Waverki 1 pt. 7,446
  2. Avatar for LS Pro Folders 22. LS Pro Folders 1 pt. 7,355
  3. Avatar for It's over 9000! 23. It's over 9000! 1 pt. 6,093
  4. Avatar for Team China 24. Team China 1 pt. 5,106
  5. Avatar for Team Germany 25. Team Germany 1 pt. 4,304
  6. Avatar for DSN @ Home 26. DSN @ Home 1 pt. 3,417
  7. Avatar for Window Group 27. Window Group 1 pt. 675
  8. Avatar for Natural Abilities 28. Natural Abilities 1 pt. 675
  1. Avatar for allie_heather47 191. allie_heather47 Lv 1 1 pt. 4,287
  2. Avatar for rufi1000 192. rufi1000 Lv 1 1 pt. 4,240
  3. Avatar for dfv219 193. dfv219 Lv 1 1 pt. 3,868
  4. Avatar for sftgfop1 194. sftgfop1 Lv 1 1 pt. 3,867
  5. Avatar for Hell_Kitty 195. Hell_Kitty Lv 1 1 pt. 3,836
  6. Avatar for MomentumJump 196. MomentumJump Lv 1 1 pt. 3,508
  7. Avatar for aspadistra 197. aspadistra Lv 1 1 pt. 3,417
  8. Avatar for Ostwald 198. Ostwald Lv 1 1 pt. 3,336
  9. Avatar for fishercat 199. fishercat Lv 1 1 pt. 3,313
  10. Avatar for Zaoman 200. Zaoman Lv 1 1 pt. 2,836

Comments

bkoep Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

The above predictions are already on the starting model (based on the horizontal lines in the above figure).
______________

Cutaway view hint:
If you hover your mouse over a segment and type shift-Q, the game will hide parts of the protein and cloud that are not in the same plane as that segment - it cuts down on how much cloud you see at one time and makes it easier to focus. Q returns to normal view.

Timo van der Laan Lv 1

This is the third repeat of an ED puzzle. I would really like to see one that hasnt been solved yet.
BTW, these kind of puzzles are now very good playable, congrats to the devs on the speed improvement since NC.

bkoep Staff Lv 1

The difficulty is finding test cases appropriate for Foldit. Most unsolved cases involve low-resolution density maps for very large proteins.

We've been running these revisited puzzles to test new ED code and recalibrate density scoring, but we're also anxious for the next unsolved density map!