Placeholder image of a protein
Icon representing a puzzle

1032: De-novo Freestyle 46: Hand-folding Round

Closed since about 11 years ago

Intermediate Overall Prediction Hand-Folding

Summary

Created
January 05, 2015
Expires
Max points
100
Description

It's been a while since our last hand-folding challenge! In this de-novo freestyle puzzle, only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be reposted with LUA scripts and sharing enabled. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.

Top groups

  1. Avatar for It's over 9000! 21. It's over 9000! 1 pt. 0
  2. Avatar for Repro-men 22. Repro-men 1 pt. 0
  3. Avatar for DSN @ Home 23. DSN @ Home 1 pt. 0
  4. Avatar for Window Group 24. Window Group 1 pt. 0
  1. Avatar for nicobul 31. nicobul Lv 1 51 pts. 8,659
  2. Avatar for frood66 32. frood66 Lv 1 50 pts. 8,655
  3. Avatar for Hiro Protagonist 33. Hiro Protagonist Lv 1 48 pts. 8,653
  4. Avatar for phi16 34. phi16 Lv 1 47 pts. 8,602
  5. Avatar for pmdpmd 35. pmdpmd Lv 1 46 pts. 8,546
  6. Avatar for Blipperman 36. Blipperman Lv 1 45 pts. 8,507
  7. Avatar for Bletchley Park 37. Bletchley Park Lv 1 44 pts. 8,469
  8. Avatar for Threeoak 38. Threeoak Lv 1 43 pts. 8,468
  9. Avatar for heather-1 39. heather-1 Lv 1 42 pts. 8,456
  10. Avatar for Bushman 40. Bushman Lv 1 41 pts. 8,446

Comments

bkoep Staff Lv 1

SS predictions from the SAM server are forthcoming, so check back soon. The starting model shows secondary structure as predicted by PSIPRED.

Skippysk8s Lv 1

I don't seem to have any SS predictions….or any idea what to do given some of these sequences. We need a hand fold puzzle for first timers. Totally lost

Skippysk8s Lv 1

there was NO SS the first time I opened this. a little overwhelming and large for a novice… Still would like a first timer only puzzle for those of us who have never hand folded. A little smaller to be managable
Thanks

bkoep Staff Lv 1

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

brgreening Lv 1

I tried to share a version of this puzzles with my group. I could not. I noticed that there is no other shared versions of this puzzle for my group. There is no "Top evolvers" for this puzzle.

Bruno Kestemont Lv 1

Hand folding round allows no sharing.
There will be a second round with scripts and sharing allowed.
If you want, you can share a picture to your group trough group chat.