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1067: Unsolved VEGF protein: Domain 1

Closed since almost 11 years ago

Intermediate Overall Prediction

Summary

Created
March 19, 2015
Expires
Max points
100
Description

The first two puzzles for this protein were able to significantly improve the structure of domain 6 of this protein, so we are giving you a different domain this time, with 5 Zhang Server predictions as starting points. Resetting the puzzle will cycle through each model. We are giving you 2 weeks to work on this puzzle, so please try out each server start. Although one server model scores better than the rest initially, it might be the furthest from the native and might not get you the most points in the end! More info in the puzzle comments.

Top groups

  1. Avatar for DSN @ Home 31. DSN @ Home 1 pt. 7,754
  2. Avatar for Geekdo 32. Geekdo 1 pt. 7,092
  3. Avatar for Maiglöckchen 33. Maiglöckchen 1 pt. 0
  1. Avatar for lamoille 151. lamoille Lv 1 6 pts. 8,374
  2. Avatar for Superphosphate 152. Superphosphate Lv 1 6 pts. 8,366
  3. Avatar for Cyberkashi 153. Cyberkashi Lv 1 6 pts. 8,360
  4. Avatar for Mohambone 154. Mohambone Lv 1 5 pts. 8,357
  5. Avatar for thekaiser 155. thekaiser Lv 1 5 pts. 8,356
  6. Avatar for Soggy Doglog 156. Soggy Doglog Lv 1 5 pts. 8,348
  7. Avatar for Pro Lapser 157. Pro Lapser Lv 1 5 pts. 8,335
  8. Avatar for NameChangeNeeded01 158. NameChangeNeeded01 Lv 1 5 pts. 8,326
  9. Avatar for saksoft2 159. saksoft2 Lv 1 5 pts. 8,319
  10. Avatar for RedStego 160. RedStego Lv 1 5 pts. 8,317

Comments

beta_helix Staff Lv 1

Please read the updated blog entry about this unsolved protein.
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The SAM server is still down, so here are the secondary structure predictions that were used for the starting chain:

The higher the number, the higher the confidence of the secondary structure prediction above it.
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Here is the link to the Zhang Server website (where you can find a lot more detailed info such as templates used and predicted per-residue accuracy for each model):
http://zhanglab.ccmb.med.umich.edu/I-TASSER/output/S218744