Placeholder image of a protein
Icon representing a puzzle

1067: Unsolved VEGF protein: Domain 1

Closed since almost 11 years ago

Intermediate Overall Prediction

Summary

Created
March 19, 2015
Expires
Max points
100
Description

The first two puzzles for this protein were able to significantly improve the structure of domain 6 of this protein, so we are giving you a different domain this time, with 5 Zhang Server predictions as starting points. Resetting the puzzle will cycle through each model. We are giving you 2 weeks to work on this puzzle, so please try out each server start. Although one server model scores better than the rest initially, it might be the furthest from the native and might not get you the most points in the end! More info in the puzzle comments.

Top groups

  1. Avatar for DSN @ Home 31. DSN @ Home 1 pt. 7,754
  2. Avatar for Geekdo 32. Geekdo 1 pt. 7,092
  3. Avatar for Maiglöckchen 33. Maiglöckchen 1 pt. 0
  1. Avatar for dcrwheeler 61. dcrwheeler Lv 1 38 pts. 8,796
  2. Avatar for smholst 62. smholst Lv 1 37 pts. 8,792
  3. Avatar for Grom 63. Grom Lv 1 37 pts. 8,790
  4. Avatar for johngran 64. johngran Lv 1 36 pts. 8,783
  5. Avatar for dettingen 65. dettingen Lv 1 36 pts. 8,768
  6. Avatar for zeroblue 66. zeroblue Lv 1 35 pts. 8,760
  7. Avatar for bamh 67. bamh Lv 1 34 pts. 8,752
  8. Avatar for froggs554 68. froggs554 Lv 1 34 pts. 8,744
  9. Avatar for Jim Fraser 69. Jim Fraser Lv 1 33 pts. 8,741
  10. Avatar for alcor29 70. alcor29 Lv 1 32 pts. 8,741

Comments

beta_helix Staff Lv 1

Please read the updated blog entry about this unsolved protein.
______

The SAM server is still down, so here are the secondary structure predictions that were used for the starting chain:

The higher the number, the higher the confidence of the secondary structure prediction above it.
______

Here is the link to the Zhang Server website (where you can find a lot more detailed info such as templates used and predicted per-residue accuracy for each model):
http://zhanglab.ccmb.med.umich.edu/I-TASSER/output/S218744