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1067: Unsolved VEGF protein: Domain 1

Closed since almost 11 years ago

Intermediate Overall Prediction

Summary


Created
March 19, 2015
Expires
Max points
100
Description

The first two puzzles for this protein were able to significantly improve the structure of domain 6 of this protein, so we are giving you a different domain this time, with 5 Zhang Server predictions as starting points. Resetting the puzzle will cycle through each model. We are giving you 2 weeks to work on this puzzle, so please try out each server start. Although one server model scores better than the rest initially, it might be the furthest from the native and might not get you the most points in the end! More info in the puzzle comments.

Top groups


  1. Avatar for Anthropic Dreams 100 pts. 9,133
  2. Avatar for Beta Folders 2. Beta Folders 86 pts. 9,133
  3. Avatar for Void Crushers 3. Void Crushers 73 pts. 9,110
  4. Avatar for Go Science 4. Go Science 62 pts. 9,076
  5. Avatar for Contenders 5. Contenders 52 pts. 9,067
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  8. Avatar for L'Alliance Francophone 8. L'Alliance Francophone 30 pts. 8,921
  9. Avatar for HMT heritage 9. HMT heritage 24 pts. 8,913
  10. Avatar for xkcd 10. xkcd 20 pts. 8,851

  1. Avatar for xtek23x 311. xtek23x Lv 1 1 pt. 7,161
  2. Avatar for salish99 312. salish99 Lv 1 1 pt. 7,092
  3. Avatar for sww9999 313. sww9999 Lv 1 1 pt. 7,046
  4. Avatar for frickinjason 314. frickinjason Lv 1 1 pt. 7,021
  5. Avatar for buli25 315. buli25 Lv 1 1 pt. 6,993
  6. Avatar for spacexplorer 316. spacexplorer Lv 1 1 pt. 6,795
  7. Avatar for darkdestroyer35 317. darkdestroyer35 Lv 1 1 pt. 6,669
  8. Avatar for TechyAngel15 318. TechyAngel15 Lv 1 1 pt. 6,642
  9. Avatar for gleep314 319. gleep314 Lv 1 1 pt. 6,358
  10. Avatar for TMT2410 320. TMT2410 Lv 1 1 pt. 6,049

Comments


beta_helix Staff Lv 1

Please read the updated blog entry about this unsolved protein.
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The SAM server is still down, so here are the secondary structure predictions that were used for the starting chain:

The higher the number, the higher the confidence of the secondary structure prediction above it.
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Here is the link to the Zhang Server website (where you can find a lot more detailed info such as templates used and predicted per-residue accuracy for each model):
http://zhanglab.ccmb.med.umich.edu/I-TASSER/output/S218744