Placeholder image of a protein
Icon representing a puzzle

1193: UMich Challenge: Refined Density

Closed since about 10 years ago

Intermediate Overall Prediction Electron Density

Summary

Created
February 11, 2016
Expires
Max points
100
Description

This puzzle is a followup to Puzzle 1152: Foldit vs. UMich Electron Density Challenge. We were impressed with many players' solutions, and our UMich collaborators have a shared a higher resolution dataset of the same protein. Foldit solutions were used to develop a higher quality electron density map from the new dataset, and we’d like to see if players can use it to further improve this model! Pay special attention to residues 20-32 and 51-64, which were unresolved in Puzzle 1152. Note that players will not be able to load in solutions from Puzzle 1152.

Top groups

  1. Avatar for Italiani Al Lavoro 11. Italiani Al Lavoro 5 pts. 29,751
  2. Avatar for xkcd 12. xkcd 4 pts. 29,582
  3. Avatar for freefolder 13. freefolder 2 pts. 29,515
  4. Avatar for Deleted group 14. Deleted group pts. 29,490
  5. Avatar for DSN @ Home 15. DSN @ Home 1 pt. 29,459
  6. Avatar for Deleted group 16. Deleted group pts. 29,279
  7. Avatar for It's over 9000! 17. It's over 9000! 1 pt. 29,244
  8. Avatar for USD_IMB 18. USD_IMB 1 pt. 29,199
  9. Avatar for Dr. Short's Molecular Lab 19. Dr. Short's Molecular Lab 1 pt. 29,163
  10. Avatar for Ms. Carter's Jr. Science Classes 20. Ms. Carter's Jr. Science Classes 1 pt. 29,051
  1. Avatar for pyrimidines 191. pyrimidines Lv 1 1 pt. 28,078
  2. Avatar for packer 192. packer Lv 1 1 pt. 28,078
  3. Avatar for Soggy Doglog 193. Soggy Doglog Lv 1 1 pt. 28,078
  4. Avatar for 18431666_Schultz 194. 18431666_Schultz Lv 1 1 pt. 28,078
  5. Avatar for TLXDYX 195. TLXDYX Lv 1 1 pt. 28,078
  6. Avatar for DamnitCats 196. DamnitCats Lv 1 1 pt. 28,078
  7. Avatar for wattsm150216 197. wattsm150216 Lv 1 1 pt. 28,078
  8. Avatar for AryehK 198. AryehK Lv 1 1 pt. 28,078
  9. Avatar for Mydogisa Toelicker 199. Mydogisa Toelicker Lv 1 1 pt. 28,078
  10. Avatar for Festering Wounds 200. Festering Wounds Lv 1 1 pt. 28,078

Comments

Anfinsen_slept_here Lv 1

I would like to know something about the model we have been given. And I suspect i am not alone.
Can you tell us what the resolution is on the ED map?

I am also curious about the R factor. Is it below 30%? Below 25%? (I confess to being a nerd, and a once-upon-a-time crystallographer.) But i think the community could benefit from some notion of how good the model is, and where we are in the process.)

Thanks.

Susume Lv 1

bkoep mentioned this in chat: "Ah, actually, the UMich students are not involved in this challenge. I forgot to mention that in the puzzle description. For this puzzle, we're more interested in how Foldit solutions compare to those of expert crystallographers."

bkoep Staff Lv 1

The resolution of this dataset is 1.8 Å.

The R factor is below 30%, so the starting model is pretty close to the correct structure.