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1193: UMich Challenge: Refined Density

Closed since about 10 years ago

Intermediate Overall Prediction Electron Density

Summary

Created
February 11, 2016
Expires
Max points
100
Description

This puzzle is a followup to Puzzle 1152: Foldit vs. UMich Electron Density Challenge. We were impressed with many players' solutions, and our UMich collaborators have a shared a higher resolution dataset of the same protein. Foldit solutions were used to develop a higher quality electron density map from the new dataset, and we’d like to see if players can use it to further improve this model! Pay special attention to residues 20-32 and 51-64, which were unresolved in Puzzle 1152. Note that players will not be able to load in solutions from Puzzle 1152.

Top groups

  1. Avatar for Something Witty 21. Something Witty 1 pt. 28,469
  2. Avatar for Natural Abilities 22. Natural Abilities 1 pt. 28,078
  3. Avatar for Deleted group 23. Deleted group pts. 28,078
  1. Avatar for pfirth 31. pfirth Lv 1 46 pts. 29,833
  2. Avatar for pmdpmd 32. pmdpmd Lv 1 45 pts. 29,832
  3. Avatar for Mike Cassidy 33. Mike Cassidy Lv 1 44 pts. 29,831
  4. Avatar for diamond_dust 34. diamond_dust Lv 1 42 pts. 29,829
  5. Avatar for cbwest 35. cbwest Lv 1 41 pts. 29,825
  6. Avatar for Bletchley Park 36. Bletchley Park Lv 1 40 pts. 29,810
  7. Avatar for Jim Fraser 37. Jim Fraser Lv 1 39 pts. 29,802
  8. Avatar for Deleted player 38. Deleted player pts. 29,798
  9. Avatar for t012 39. t012 Lv 1 37 pts. 29,790
  10. Avatar for Skippysk8s 40. Skippysk8s Lv 1 36 pts. 29,785

Comments

Anfinsen_slept_here Lv 1

I would like to know something about the model we have been given. And I suspect i am not alone.
Can you tell us what the resolution is on the ED map?

I am also curious about the R factor. Is it below 30%? Below 25%? (I confess to being a nerd, and a once-upon-a-time crystallographer.) But i think the community could benefit from some notion of how good the model is, and where we are in the process.)

Thanks.

Susume Lv 1

bkoep mentioned this in chat: "Ah, actually, the UMich students are not involved in this challenge. I forgot to mention that in the puzzle description. For this puzzle, we're more interested in how Foldit solutions compare to those of expert crystallographers."

bkoep Staff Lv 1

The resolution of this dataset is 1.8 Å.

The R factor is below 30%, so the starting model is pretty close to the correct structure.