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1310: Revisiting Puzzle 79: Pheromone

Closed since over 9 years ago

Intermediate Overall Prediction

Summary

Created
November 29, 2016
Expires
Max points
100
Description

This is a throwback puzzle to the early days of Foldit. This pheromone protein is secreted by the protist E. raikovi to initiate conjugation, the exchange of genetic material between two cells. This protein contains ten cysteine residues that oxidize to form five disulfide bonds. We are revisiting old Foldit puzzles so we can see how useful the recent additions to the game have been.



Sequence:


GECEQCFSDGGDCTTCFNNGTGPCANCLAGYPAGCSNSDCTAFLSQCYGGC

Top groups

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  8. Avatar for ZeroLeak7 28. ZeroLeak7 Lv 1 49 pts. 9,898
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  10. Avatar for TomTaylor 30. TomTaylor Lv 1 47 pts. 9,889

Comments

Aubade01 Lv 1

I my structure, and I believe in others also, there are two hairpins between segments 15 and 20. It does not seem to me that in the native fold nature would put four right angles in a loop structure. I have seen this in many recent structures and it appears the database is overly favoring hairpins.

Aubade01(00)