1310: Revisiting Puzzle 79: Pheromone

Closed since over 9 years ago

Summary

• Created: November 29, 2016
• Expires: December 06, 2016 at 18:00 UTC
• Max points: 100

Description

This is a throwback puzzle to the early days of Foldit. This pheromone protein is secreted by the protist E. raikovi to initiate conjugation, the exchange of genetic material between two cells. This protein contains ten cysteine residues that oxidize to form five disulfide bonds. We are revisiting old Foldit puzzles so we can see how useful the recent additions to the game have been.



Sequence:

GECEQCFSDGGDCTTCFNNGTGPCANCLAGYPAGCSNSDCTAFLSQCYGGC

Top groups

• 1. Beta Folders 100 pts. 10,021
• 2. Contenders 81 pts. 10,003
• 3. Void Crushers 65 pts. 9,995
• 4. Go Science 52 pts. 9,983
• 5. Anthropic Dreams 41 pts. 9,983
• 6. Gargleblasters 32 pts. 9,948
• 7. L'Alliance Francophone 24 pts. 9,942
• 8. HMT heritage 18 pts. 9,720
• 9. xkcd 14 pts. 9,703
• 10. Italiani Al Lavoro 10 pts. 9,603

Top soloists

• 1. retiredmichael 100 pts. 10,012
• 2. LociOiling 98 pts. 10,007
• 3. gitwut 96 pts. 10,003
• 4. Timo van der Laan 93 pts. 9,995
• 5. Bruno Kestemont 91 pts. 9,983
• 6. markm457 89 pts. 9,983
• 7. g_b 87 pts. 9,978
• 8. fiendish_ghoul 84 pts. 9,978
• 9. Aubade01 82 pts. 9,975
• 10. bertro 80 pts. 9,972

Comments

[Aubade01]

I my structure, and I believe in others also, there are two hairpins between segments 15 and 20. It does not seem to me that in the native fold nature would put four right angles in a loop structure. I have seen this in many recent structures and it appears the database is overly favoring hairpins.

Aubade01(00)