Placeholder image of a protein
Icon representing a puzzle

1310: Revisiting Puzzle 79: Pheromone

Closed since over 9 years ago

Intermediate Overall Prediction

Summary

Created
November 29, 2016
Expires
Max points
100
Description

This is a throwback puzzle to the early days of Foldit. This pheromone protein is secreted by the protist E. raikovi to initiate conjugation, the exchange of genetic material between two cells. This protein contains ten cysteine residues that oxidize to form five disulfide bonds. We are revisiting old Foldit puzzles so we can see how useful the recent additions to the game have been.



Sequence:


GECEQCFSDGGDCTTCFNNGTGPCANCLAGYPAGCSNSDCTAFLSQCYGGC

Top groups

  1. Avatar for Beta Folders
    1. Beta Folders
    100 pts. 10,021
  2. Avatar for Contenders 2. Contenders 81 pts. 10,003
  3. Avatar for Void Crushers 3. Void Crushers 65 pts. 9,995
  4. Avatar for Go Science 4. Go Science 52 pts. 9,983
  5. Avatar for Anthropic Dreams 5. Anthropic Dreams 41 pts. 9,983
  6. Avatar for Gargleblasters 6. Gargleblasters 32 pts. 9,948
  7. Avatar for L'Alliance Francophone 7. L'Alliance Francophone 24 pts. 9,942
  8. Avatar for HMT heritage 8. HMT heritage 18 pts. 9,720
  9. Avatar for xkcd 9. xkcd 14 pts. 9,703
  10. Avatar for Italiani Al Lavoro 10. Italiani Al Lavoro 10 pts. 9,603
  1. Avatar for ek2ma 181. ek2ma Lv 1 1 pt. 7,743
  2. Avatar for ababu912 182. ababu912 Lv 1 1 pt. 7,742
  3. Avatar for Fatecallsuponus 183. Fatecallsuponus Lv 1 1 pt. 7,736
  4. Avatar for bak45239 184. bak45239 Lv 1 1 pt. 7,728
  5. Avatar for Vermillion03124 185. Vermillion03124 Lv 1 1 pt. 7,722
  6. Avatar for layerofgauze 186. layerofgauze Lv 1 1 pt. 7,707
  7. Avatar for karli.weise 187. karli.weise Lv 1 1 pt. 7,677
  8. Avatar for rakei 188. rakei Lv 1 1 pt. 7,635
  9. Avatar for eecayo 189. eecayo Lv 1 1 pt. 7,582
  10. Avatar for truchuu.doan 190. truchuu.doan Lv 1 1 pt. 7,420

Comments

Aubade01 Lv 1

I my structure, and I believe in others also, there are two hairpins between segments 15 and 20. It does not seem to me that in the native fold nature would put four right angles in a loop structure. I have seen this in many recent structures and it appears the database is overly favoring hairpins.

Aubade01(00)