Placeholder image of a protein
Icon representing a puzzle

1310: Revisiting Puzzle 79: Pheromone

Closed since over 9 years ago

Intermediate Overall Prediction

Summary

Created
November 29, 2016
Expires
Max points
100
Description

This is a throwback puzzle to the early days of Foldit. This pheromone protein is secreted by the protist E. raikovi to initiate conjugation, the exchange of genetic material between two cells. This protein contains ten cysteine residues that oxidize to form five disulfide bonds. We are revisiting old Foldit puzzles so we can see how useful the recent additions to the game have been.



Sequence:


GECEQCFSDGGDCTTCFNNGTGPCANCLAGYPAGCSNSDCTAFLSQCYGGC

Top groups

  1. Avatar for Beta Folders
    1. Beta Folders
    100 pts. 10,021
  2. Avatar for Contenders 2. Contenders 81 pts. 10,003
  3. Avatar for Void Crushers 3. Void Crushers 65 pts. 9,995
  4. Avatar for Go Science 4. Go Science 52 pts. 9,983
  5. Avatar for Anthropic Dreams 5. Anthropic Dreams 41 pts. 9,983
  6. Avatar for Gargleblasters 6. Gargleblasters 32 pts. 9,948
  7. Avatar for L'Alliance Francophone 7. L'Alliance Francophone 24 pts. 9,942
  8. Avatar for HMT heritage 8. HMT heritage 18 pts. 9,720
  9. Avatar for xkcd 9. xkcd 14 pts. 9,703
  10. Avatar for Italiani Al Lavoro 10. Italiani Al Lavoro 10 pts. 9,603
  1. Avatar for smilingone 61. smilingone Lv 1 18 pts. 9,708
  2. Avatar for fryguy 62. fryguy Lv 1 17 pts. 9,703
  3. Avatar for alcor29 63. alcor29 Lv 1 17 pts. 9,694
  4. Avatar for diamonddays 64. diamonddays Lv 1 16 pts. 9,692
  5. Avatar for JayD7217 65. JayD7217 Lv 1 16 pts. 9,679
  6. Avatar for Vinara 66. Vinara Lv 1 15 pts. 9,670
  7. Avatar for WBarme1234 67. WBarme1234 Lv 1 14 pts. 9,668
  8. Avatar for Jim Fraser 68. Jim Fraser Lv 1 14 pts. 9,662
  9. Avatar for manu8170 69. manu8170 Lv 1 14 pts. 9,659
  10. Avatar for pfirth 70. pfirth Lv 1 13 pts. 9,651

Comments

Aubade01 Lv 1

I my structure, and I believe in others also, there are two hairpins between segments 15 and 20. It does not seem to me that in the native fold nature would put four right angles in a loop structure. I have seen this in many recent structures and it appears the database is overly favoring hairpins.

Aubade01(00)