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1499: Symmetric Dimer Design: Hydrogen Bond Networks

Closed since almost 8 years ago

Intermediate

Summary

Created
March 20, 2018
Expires
Max points
100
Description

This symmetric design puzzle has C2 symmetry, with two symmetric chains. The H-bond Network Filter encourages players to bury satisfied H-bond networks at the interface between the two chains. There are several other filters in effect; see the puzzle comments for details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!



Note: This puzzle was closed early due to a problematic filter, and reposted as Puzzle 1499b.

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Comments

Mike Cassidy Lv 1

I just sent to Scientist what i think maybe a bug. I was making sheets -7- and the last three can not be moved by the move tool.

Timo van der Laan Lv 1

As I wrote, after saving and reloading the shadow was the same as the original. The original did not change there, the shadow became equal to the original. So a very strange glitch. And the scientists will not have info from the save I think.

bkoep Staff Lv 1

Thanks for clarifying—I had assumed the threshold issue was the source of all the problems. This looks like it might be a bug. The filter is set at 25% core, but it's behaving like it expects 50% core.

This should be easy enough to get around. We'll close and repost the puzzle.