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Protein Design Sandbox

Closed since about 4 years ago

Beginner

Summary


Created
March 22, 2020
Expires
Max points
100
Description

Experiment with protein design! We've disabled many of the restrictions in normal Science puzzles, so players have access to all protein designs tools, and may insert and delete any number of residues. Foldit scientists do not check the solutions from this puzzle, and playing this puzzle will not affect your global or category rankings.



Two common protein design Objectives are available, but they will not award any bonuses or penalties. The Core Existence Objective checks to see if 30% of residues are buried in the protein core, away from the water surrounding the protein. The Ideal Loops Objective looks for loops with problematic backbone folds. If you build an especially large protein, try disabling these Objectives to improve Foldit's performance.

Top groups


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  6. Avatar for Italiani Al Lavoro 27. Italiani Al Lavoro 17 pts. 10,161
  7. Avatar for NMHU Biol4230 Spr 20 28. NMHU Biol4230 Spr 20 16 pts. 9,861
  8. Avatar for Deleted group 29. Deleted group pts. 9,846
  9. Avatar for GENE 433 30. GENE 433 14 pts. 9,732

  1. Avatar for jschroeter 291. jschroeter Lv 1 35 pts. 9,599
  2. Avatar for faues 292. faues Lv 1 35 pts. 9,596
  3. Avatar for buggo 293. buggo Lv 1 35 pts. 9,595
  4. Avatar for MurloW 294. MurloW Lv 1 35 pts. 9,593
  5. Avatar for sudochmod 295. sudochmod Lv 1 35 pts. 9,590
  6. Avatar for Dane2020 296. Dane2020 Lv 1 34 pts. 9,573
  7. Avatar for wosser1 297. wosser1 Lv 1 34 pts. 9,563
  8. Avatar for Altiboum 298. Altiboum Lv 1 34 pts. 9,563
  9. Avatar for puxatudo 299. puxatudo Lv 1 34 pts. 9,547
  10. Avatar for SaraL 300. SaraL Lv 1 34 pts. 9,537

Comments


DoctorSockrates Lv 1

I was wondering when something like this would turn up. Glad to see an unrestricted proving ground for future projects.

KALYPSO Lv 1

Soap,,,,breaks the faty around the cell ,,,hmmmmm,,,puzzle that,,,just saying,,,try it

Bautho Lv 1

I don't know what is / I did wrong, but I designed a fold - perfectly fine, but after a while I wiggled, and one part of the protein will start to unfold (the helix is not a helix anymore) and the score goes down instead of up.
I sent the structure to scientists - if you could reproduce that behavior would be interesting! :)