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Protein Design Sandbox

Closed since about 4 years ago

Beginner

Summary


Created
March 22, 2020
Expires
Max points
100
Description

Experiment with protein design! We've disabled many of the restrictions in normal Science puzzles, so players have access to all protein designs tools, and may insert and delete any number of residues. Foldit scientists do not check the solutions from this puzzle, and playing this puzzle will not affect your global or category rankings.



Two common protein design Objectives are available, but they will not award any bonuses or penalties. The Core Existence Objective checks to see if 30% of residues are buried in the protein core, away from the water surrounding the protein. The Ideal Loops Objective looks for loops with problematic backbone folds. If you build an especially large protein, try disabling these Objectives to improve Foldit's performance.

Top groups


  1. Avatar for Olsztynek 21. Olsztynek 28 pts. 10,548
  2. Avatar for SETI.Germany 23. SETI.Germany 24 pts. 10,454
  3. Avatar for Rechenkraft.net 24. Rechenkraft.net 22 pts. 10,406
  4. Avatar for Coastal Biochemistry 25. Coastal Biochemistry 20 pts. 10,295
  5. Avatar for Foldit Staff 26. Foldit Staff 19 pts. 10,249
  6. Avatar for Italiani Al Lavoro 27. Italiani Al Lavoro 17 pts. 10,161
  7. Avatar for NMHU Biol4230 Spr 20 28. NMHU Biol4230 Spr 20 16 pts. 9,861
  8. Avatar for Deleted group 29. Deleted group pts. 9,846
  9. Avatar for GENE 433 30. GENE 433 14 pts. 9,732

  1. Avatar for Pyxicephalus 371. Pyxicephalus Lv 1 25 pts. 9,175
  2. Avatar for okaits7534 372. okaits7534 Lv 1 25 pts. 9,173
  3. Avatar for boccaccio 373. boccaccio Lv 1 25 pts. 9,160
  4. Avatar for alt52 374. alt52 Lv 1 25 pts. 9,157
  5. Avatar for jacob_n 375. jacob_n Lv 1 25 pts. 9,156
  6. Avatar for sherlomck_7 376. sherlomck_7 Lv 1 25 pts. 9,154
  7. Avatar for PseudoMathematician 377. PseudoMathematician Lv 1 25 pts. 9,149
  8. Avatar for papasmurf01 378. papasmurf01 Lv 1 25 pts. 9,147
  9. Avatar for Anny 8324 379. Anny 8324 Lv 1 24 pts. 9,138
  10. Avatar for kurenan 380. kurenan Lv 1 24 pts. 9,132

Comments


DoctorSockrates Lv 1

I was wondering when something like this would turn up. Glad to see an unrestricted proving ground for future projects.

KALYPSO Lv 1

Soap,,,,breaks the faty around the cell ,,,hmmmmm,,,puzzle that,,,just saying,,,try it

Bautho Lv 1

I don't know what is / I did wrong, but I designed a fold - perfectly fine, but after a while I wiggled, and one part of the protein will start to unfold (the helix is not a helix anymore) and the score goes down instead of up.
I sent the structure to scientists - if you could reproduce that behavior would be interesting! :)