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Protein Design Sandbox

Closed since about 4 years ago

Beginner

Summary


Created
March 22, 2020
Expires
Max points
100
Description

Experiment with protein design! We've disabled many of the restrictions in normal Science puzzles, so players have access to all protein designs tools, and may insert and delete any number of residues. Foldit scientists do not check the solutions from this puzzle, and playing this puzzle will not affect your global or category rankings.



Two common protein design Objectives are available, but they will not award any bonuses or penalties. The Core Existence Objective checks to see if 30% of residues are buried in the protein core, away from the water surrounding the protein. The Ideal Loops Objective looks for loops with problematic backbone folds. If you build an especially large protein, try disabling these Objectives to improve Foldit's performance.

Top groups


  1. Avatar for BIOL 4030 Winter 2020 31. BIOL 4030 Winter 2020 13 pts. 9,653
  2. Avatar for Spain Team 32. Spain Team 12 pts. 9,563
  3. Avatar for BIOF215 33. BIOF215 11 pts. 9,446
  4. Avatar for METU-BIN 34. METU-BIN 10 pts. 9,343
  5. Avatar for MAB_STEM 35. MAB_STEM 9 pts. 9,297
  6. Avatar for Mojo Risin' 37. Mojo Risin' 7 pts. 9,070
  7. Avatar for Trinity Biology 38. Trinity Biology 7 pts. 8,807
  8. Avatar for BIOL 308L 39. BIOL 308L 6 pts. 8,793
  9. Avatar for G1051331 40. G1051331 6 pts. 8,708

  1. Avatar for retiredmichael 1261. retiredmichael Lv 1 1 pt. 0
  2. Avatar for inuyasha10121 1262. inuyasha10121 Lv 1 1 pt. 0
  3. Avatar for busywong 1263. busywong Lv 1 1 pt. 0
  4. Avatar for destineesandy1 1264. destineesandy1 Lv 1 1 pt. 0
  5. Avatar for molleke 1265. molleke Lv 1 1 pt. 0
  6. Avatar for seanrjohnson 1266. seanrjohnson Lv 1 1 pt. 0
  7. Avatar for asg233 1267. asg233 Lv 1 1 pt. 0
  8. Avatar for f.khoury 1268. f.khoury Lv 1 1 pt. 0
  9. Avatar for ZeroLeak7 1269. ZeroLeak7 Lv 1 1 pt. 0
  10. Avatar for ruben flores g 1270. ruben flores g Lv 1 1 pt. 0

Comments


DoctorSockrates Lv 1

I was wondering when something like this would turn up. Glad to see an unrestricted proving ground for future projects.

KALYPSO Lv 1

Soap,,,,breaks the faty around the cell ,,,hmmmmm,,,puzzle that,,,just saying,,,try it

Bautho Lv 1

I don't know what is / I did wrong, but I designed a fold - perfectly fine, but after a while I wiggled, and one part of the protein will start to unfold (the helix is not a helix anymore) and the score goes down instead of up.
I sent the structure to scientists - if you could reproduce that behavior would be interesting! :)