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Protein Design Sandbox

Closed since about 4 years ago

Beginner

Summary

Created
March 22, 2020
Expires
Max points
100
Description

Experiment with protein design! We've disabled many of the restrictions in normal Science puzzles, so players have access to all protein designs tools, and may insert and delete any number of residues. Foldit scientists do not check the solutions from this puzzle, and playing this puzzle will not affect your global or category rankings.



Two common protein design Objectives are available, but they will not award any bonuses or penalties. The Core Existence Objective checks to see if 30% of residues are buried in the protein core, away from the water surrounding the protein. The Ideal Loops Objective looks for loops with problematic backbone folds. If you build an especially large protein, try disabling these Objectives to improve Foldit's performance.

Top groups

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  4. Avatar for METU-BIN 34. METU-BIN 10 pts. 9,343
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  3. Avatar for point40421 1333. point40421 Lv 1 1 pt. 0
  4. Avatar for baltx 1334. baltx Lv 1 1 pt. 0
  5. Avatar for Yoshima 1335. Yoshima Lv 1 1 pt. 0
  6. Avatar for HuyPham 1336. HuyPham Lv 1 1 pt. 0
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  8. Avatar for pitermarried 1338. pitermarried Lv 1 1 pt. 0
  9. Avatar for jules277 1339. jules277 Lv 1 1 pt. 0
  10. Avatar for maxi369 1340. maxi369 Lv 1 1 pt. 0

Comments

DoctorSockrates Lv 1

I was wondering when something like this would turn up. Glad to see an unrestricted proving ground for future projects.

KALYPSO Lv 1

Soap,,,,breaks the faty around the cell ,,,hmmmmm,,,puzzle that,,,just saying,,,try it

Bautho Lv 1

I don't know what is / I did wrong, but I designed a fold - perfectly fine, but after a while I wiggled, and one part of the protein will start to unfold (the helix is not a helix anymore) and the score goes down instead of up.
I sent the structure to scientists - if you could reproduce that behavior would be interesting! :)