Placeholder image of a protein
Icon representing a puzzle

Protein Design Sandbox

Closed since almost 4 years ago

Beginner

Summary

Created
March 22, 2020
Expires
Max points
100
Description

Experiment with protein design! We've disabled many of the restrictions in normal Science puzzles, so players have access to all protein designs tools, and may insert and delete any number of residues. Foldit scientists do not check the solutions from this puzzle, and playing this puzzle will not affect your global or category rankings.



Two common protein design Objectives are available, but they will not award any bonuses or penalties. The Core Existence Objective checks to see if 30% of residues are buried in the protein core, away from the water surrounding the protein. The Ideal Loops Objective looks for loops with problematic backbone folds. If you build an especially large protein, try disabling these Objectives to improve Foldit's performance.

Top groups

  1. Avatar for Deleted group 41. Deleted group pts. 8,693
  2. Avatar for Richard Dawkins Foundation 42. Richard Dawkins Foundation 5 pts. 8,665
  3. Avatar for Mercer_F20_BMB465_Crawford 43. Mercer_F20_BMB465_Crawford 4 pts. 8,579
  4. Avatar for Deleted group 44. Deleted group pts. 8,418
  5. Avatar for Columbia Univ CHEN 4800 Summer 2021 45. Columbia Univ CHEN 4800 Summer 2021 3 pts. 8,407
  6. Avatar for Team Canada 46. Team Canada 3 pts. 8,406
  7. Avatar for HMT heritage 47. HMT heritage 3 pts. 8,388
  8. Avatar for GBHS BMAH kids 48. GBHS BMAH kids 3 pts. 8,145
  9. Avatar for bmd 49. bmd 2 pts. 7,780
  10. Avatar for Titans of Biology 50. Titans of Biology 2 pts. 7,684
  1. Avatar for phi16
    1. phi16 Lv 1
    100 pts. 46,086
  2. Avatar for akaaka 2. akaaka Lv 1 100 pts. 45,877
  3. Avatar for CharlieFortsConscience 3. CharlieFortsConscience Lv 1 100 pts. 38,435
  4. Avatar for LastAndroid 4. LastAndroid Lv 1 100 pts. 37,120
  5. Avatar for pvc78 5. pvc78 Lv 1 99 pts. 32,500
  6. Avatar for Enzyme 6. Enzyme Lv 1 99 pts. 32,421
  7. Avatar for Miguelan15 7. Miguelan15 Lv 1 99 pts. 31,466
  8. Avatar for ShadowTactics 8. ShadowTactics Lv 1 98 pts. 29,493
  9. Avatar for zo3xiaJonWeinberg 9. zo3xiaJonWeinberg Lv 1 98 pts. 29,032
  10. Avatar for snowleopard94 10. snowleopard94 Lv 1 98 pts. 28,794

Comments

DoctorSockrates Lv 1

I was wondering when something like this would turn up. Glad to see an unrestricted proving ground for future projects.

KALYPSO Lv 1

Soap,,,,breaks the faty around the cell ,,,hmmmmm,,,puzzle that,,,just saying,,,try it

Bautho Lv 1

I don't know what is / I did wrong, but I designed a fold - perfectly fine, but after a while I wiggled, and one part of the protein will start to unfold (the helix is not a helix anymore) and the score goes down instead of up.
I sent the structure to scientists - if you could reproduce that behavior would be interesting! :)