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Protein Design Sandbox

Closed since about 4 years ago

Beginner

Summary

Created
March 22, 2020
Expires
Max points
100
Description

Experiment with protein design! We've disabled many of the restrictions in normal Science puzzles, so players have access to all protein designs tools, and may insert and delete any number of residues. Foldit scientists do not check the solutions from this puzzle, and playing this puzzle will not affect your global or category rankings.



Two common protein design Objectives are available, but they will not award any bonuses or penalties. The Core Existence Objective checks to see if 30% of residues are buried in the protein core, away from the water surrounding the protein. The Ideal Loops Objective looks for loops with problematic backbone folds. If you build an especially large protein, try disabling these Objectives to improve Foldit's performance.

Top groups

  1. Avatar for Camillo203LSec12 61. Camillo203LSec12 1 pt. 2,468
  2. Avatar for Fox Folds 62. Fox Folds 1 pt. 2,376
  3. Avatar for Chrestensen CHEM 3500 F2020 63. Chrestensen CHEM 3500 F2020 1 pt. 2,229
  4. Avatar for DU Proteins S20 64. DU Proteins S20 1 pt. 0
  5. Avatar for Gruppo notte dei ricercatori 65. Gruppo notte dei ricercatori 1 pt. 0
  6. Avatar for Deleted group 66. Deleted group pts. 0
  7. Avatar for Eastern Prehistoric Force 67. Eastern Prehistoric Force 1 pt. 0
  8. Avatar for IB BIO 1 68. IB BIO 1 1 pt. 0
  9. Avatar for Texas Tech Red Folders 69. Texas Tech Red Folders 1 pt. 0
  10. Avatar for incognito group 70. incognito group 1 pt. 0
  1. Avatar for tedol20 441. tedol20 Lv 1 19 pts. 8,793
  2. Avatar for dead.king 442. dead.king Lv 1 19 pts. 8,784
  3. Avatar for RKAredknightalpha 443. RKAredknightalpha Lv 1 18 pts. 8,783
  4. Avatar for SueCerlier 444. SueCerlier Lv 1 18 pts. 8,779
  5. Avatar for hornfamily 445. hornfamily Lv 1 18 pts. 8,777
  6. Avatar for ChrisKonrad 446. ChrisKonrad Lv 1 18 pts. 8,770
  7. Avatar for juliajcameron 447. juliajcameron Lv 1 18 pts. 8,766
  8. Avatar for Cosmos000 448. Cosmos000 Lv 1 18 pts. 8,766
  9. Avatar for HyeongseobShin 449. HyeongseobShin Lv 1 18 pts. 8,765
  10. Avatar for David_Mattern 450. David_Mattern Lv 1 18 pts. 8,763

Comments

DoctorSockrates Lv 1

I was wondering when something like this would turn up. Glad to see an unrestricted proving ground for future projects.

KALYPSO Lv 1

Soap,,,,breaks the faty around the cell ,,,hmmmmm,,,puzzle that,,,just saying,,,try it

Bautho Lv 1

I don't know what is / I did wrong, but I designed a fold - perfectly fine, but after a while I wiggled, and one part of the protein will start to unfold (the helix is not a helix anymore) and the score goes down instead of up.
I sent the structure to scientists - if you could reproduce that behavior would be interesting! :)