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Protein Design Sandbox

Closed since about 4 years ago

Beginner

Summary

Created
March 22, 2020
Expires
Max points
100
Description

Experiment with protein design! We've disabled many of the restrictions in normal Science puzzles, so players have access to all protein designs tools, and may insert and delete any number of residues. Foldit scientists do not check the solutions from this puzzle, and playing this puzzle will not affect your global or category rankings.



Two common protein design Objectives are available, but they will not award any bonuses or penalties. The Core Existence Objective checks to see if 30% of residues are buried in the protein core, away from the water surrounding the protein. The Ideal Loops Objective looks for loops with problematic backbone folds. If you build an especially large protein, try disabling these Objectives to improve Foldit's performance.

Top groups

  1. Avatar for Camillo203LSec12 61. Camillo203LSec12 1 pt. 2,468
  2. Avatar for Fox Folds 62. Fox Folds 1 pt. 2,376
  3. Avatar for Chrestensen CHEM 3500 F2020 63. Chrestensen CHEM 3500 F2020 1 pt. 2,229
  4. Avatar for DU Proteins S20 64. DU Proteins S20 1 pt. 0
  5. Avatar for Gruppo notte dei ricercatori 65. Gruppo notte dei ricercatori 1 pt. 0
  6. Avatar for Deleted group 66. Deleted group pts. 0
  7. Avatar for Eastern Prehistoric Force 67. Eastern Prehistoric Force 1 pt. 0
  8. Avatar for IB BIO 1 68. IB BIO 1 1 pt. 0
  9. Avatar for Texas Tech Red Folders 69. Texas Tech Red Folders 1 pt. 0
  10. Avatar for incognito group 70. incognito group 1 pt. 0
  1. Avatar for ProteinStand 861. ProteinStand Lv 1 2 pts. 2,585
  2. Avatar for firegod 862. firegod Lv 1 2 pts. 2,585
  3. Avatar for karenh 863. karenh Lv 1 2 pts. 2,585
  4. Avatar for rockcrusherninja 864. rockcrusherninja Lv 1 2 pts. 2,585
  5. Avatar for Ivan1248 865. Ivan1248 Lv 1 2 pts. 2,585
  6. Avatar for NatureBio 866. NatureBio Lv 1 2 pts. 2,585
  7. Avatar for Aromero13 867. Aromero13 Lv 1 2 pts. 2,585
  8. Avatar for Lassy33 868. Lassy33 Lv 1 2 pts. 2,585
  9. Avatar for HellaciousHaze 869. HellaciousHaze Lv 1 2 pts. 2,585
  10. Avatar for steveB 870. steveB Lv 1 2 pts. 2,585

Comments

DoctorSockrates Lv 1

I was wondering when something like this would turn up. Glad to see an unrestricted proving ground for future projects.

KALYPSO Lv 1

Soap,,,,breaks the faty around the cell ,,,hmmmmm,,,puzzle that,,,just saying,,,try it

Bautho Lv 1

I don't know what is / I did wrong, but I designed a fold - perfectly fine, but after a while I wiggled, and one part of the protein will start to unfold (the helix is not a helix anymore) and the score goes down instead of up.
I sent the structure to scientists - if you could reproduce that behavior would be interesting! :)