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Protein Design Sandbox

Closed since about 4 years ago

Beginner

Summary

Created
March 22, 2020
Expires
Max points
100
Description

Experiment with protein design! We've disabled many of the restrictions in normal Science puzzles, so players have access to all protein designs tools, and may insert and delete any number of residues. Foldit scientists do not check the solutions from this puzzle, and playing this puzzle will not affect your global or category rankings.



Two common protein design Objectives are available, but they will not award any bonuses or penalties. The Core Existence Objective checks to see if 30% of residues are buried in the protein core, away from the water surrounding the protein. The Ideal Loops Objective looks for loops with problematic backbone folds. If you build an especially large protein, try disabling these Objectives to improve Foldit's performance.

Top groups

  1. Avatar for Anthropic Dreams
    1. Anthropic Dreams
    100 pts. 46,086
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  4. Avatar for Beta Folders 4. Beta Folders 84 pts. 32,500
  5. Avatar for BOINC@Poland 5. BOINC@Poland 80 pts. 29,493
  6. Avatar for Team China 6. Team China 75 pts. 29,032
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  10. Avatar for Penny-Arcade 10. Penny-Arcade 58 pts. 22,049
  1. Avatar for jzbradley 1341. jzbradley Lv 1 1 pt. 0
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  3. Avatar for Crispanchito 1343. Crispanchito Lv 1 1 pt. 0
  4. Avatar for roodo244 1344. roodo244 Lv 1 1 pt. 0
  5. Avatar for Hiaci 1345. Hiaci Lv 1 1 pt. 0
  6. Avatar for Luke2020 1346. Luke2020 Lv 1 1 pt. 0
  7. Avatar for Dragonite 1347. Dragonite Lv 1 1 pt. 0
  8. Avatar for Bletchley Park 1348. Bletchley Park Lv 1 1 pt. 0
  9. Avatar for Victorius68GG 1349. Victorius68GG Lv 1 1 pt. 0
  10. Avatar for macronsucedesours 1350. macronsucedesours Lv 1 1 pt. 0

Comments

DoctorSockrates Lv 1

I was wondering when something like this would turn up. Glad to see an unrestricted proving ground for future projects.

KALYPSO Lv 1

Soap,,,,breaks the faty around the cell ,,,hmmmmm,,,puzzle that,,,just saying,,,try it

Bautho Lv 1

I don't know what is / I did wrong, but I designed a fold - perfectly fine, but after a while I wiggled, and one part of the protein will start to unfold (the helix is not a helix anymore) and the score goes down instead of up.
I sent the structure to scientists - if you could reproduce that behavior would be interesting! :)