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Protein Design Sandbox

Closed since almost 4 years ago

Beginner

Summary

Created
March 22, 2020
Expires
Max points
100
Description

Experiment with protein design! We've disabled many of the restrictions in normal Science puzzles, so players have access to all protein designs tools, and may insert and delete any number of residues. Foldit scientists do not check the solutions from this puzzle, and playing this puzzle will not affect your global or category rankings.



Two common protein design Objectives are available, but they will not award any bonuses or penalties. The Core Existence Objective checks to see if 30% of residues are buried in the protein core, away from the water surrounding the protein. The Ideal Loops Objective looks for loops with problematic backbone folds. If you build an especially large protein, try disabling these Objectives to improve Foldit's performance.

Top groups

  1. Avatar for Anthropic Dreams
    1. Anthropic Dreams
    100 pts. 46,086
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  4. Avatar for Beta Folders 4. Beta Folders 84 pts. 32,500
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  7. Avatar for Go Science 7. Go Science 70 pts. 25,493
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  10. Avatar for Penny-Arcade 10. Penny-Arcade 58 pts. 22,049
  1. Avatar for gcaruth 1471. gcaruth Lv 1 1 pt. 0
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  3. Avatar for dmtalbot 1473. dmtalbot Lv 1 1 pt. 0
  4. Avatar for spreston03 1474. spreston03 Lv 1 1 pt. 0
  5. Avatar for Alyssa Carrillo 1475. Alyssa Carrillo Lv 1 1 pt. 0
  6. Avatar for alienx 1476. alienx Lv 1 1 pt. 0
  7. Avatar for Philly1991 1477. Philly1991 Lv 1 1 pt. 0
  8. Avatar for Pascal2002 1478. Pascal2002 Lv 1 1 pt. 0
  9. Avatar for sztumka 1479. sztumka Lv 1 1 pt. 0
  10. Avatar for LionTec 1480. LionTec Lv 1 1 pt. 0

Comments

DoctorSockrates Lv 1

I was wondering when something like this would turn up. Glad to see an unrestricted proving ground for future projects.

KALYPSO Lv 1

Soap,,,,breaks the faty around the cell ,,,hmmmmm,,,puzzle that,,,just saying,,,try it

Bautho Lv 1

I don't know what is / I did wrong, but I designed a fold - perfectly fine, but after a while I wiggled, and one part of the protein will start to unfold (the helix is not a helix anymore) and the score goes down instead of up.
I sent the structure to scientists - if you could reproduce that behavior would be interesting! :)