Placeholder image of a protein
Icon representing a puzzle

Protein Design Sandbox

Closed since about 4 years ago

Beginner

Summary


Created
March 22, 2020
Expires
Max points
100
Description

Experiment with protein design! We've disabled many of the restrictions in normal Science puzzles, so players have access to all protein designs tools, and may insert and delete any number of residues. Foldit scientists do not check the solutions from this puzzle, and playing this puzzle will not affect your global or category rankings.



Two common protein design Objectives are available, but they will not award any bonuses or penalties. The Core Existence Objective checks to see if 30% of residues are buried in the protein core, away from the water surrounding the protein. The Ideal Loops Objective looks for loops with problematic backbone folds. If you build an especially large protein, try disabling these Objectives to improve Foldit's performance.

Top groups


  1. Avatar for Anthropic Dreams 100 pts. 46,086
  2. Avatar for Contenders 2. Contenders 95 pts. 40,014
  3. Avatar for Gargleblasters 3. Gargleblasters 90 pts. 37,120
  4. Avatar for Beta Folders 4. Beta Folders 84 pts. 32,500
  5. Avatar for BOINC@Poland 5. BOINC@Poland 80 pts. 29,493
  6. Avatar for Team China 6. Team China 75 pts. 29,032
  7. Avatar for Go Science 7. Go Science 70 pts. 25,493
  8. Avatar for Russian team 8. Russian team 66 pts. 25,114
  9. Avatar for Australia 9. Australia 62 pts. 22,809
  10. Avatar for Penny-Arcade 10. Penny-Arcade 58 pts. 22,049

  1. Avatar for AlfaKilo 731. AlfaKilo Lv 1 4 pts. 3,901
  2. Avatar for rafe_barratt 732. rafe_barratt Lv 1 4 pts. 3,897
  3. Avatar for GDescanzo 733. GDescanzo Lv 1 4 pts. 3,897
  4. Avatar for 01010000 01001010 734. 01010000 01001010 Lv 1 4 pts. 3,892
  5. Avatar for ekrause1406 735. ekrause1406 Lv 1 4 pts. 3,877
  6. Avatar for GLOwneRY 736. GLOwneRY Lv 1 4 pts. 3,837
  7. Avatar for Domaradzcy 737. Domaradzcy Lv 1 4 pts. 3,715
  8. Avatar for sspoerri 738. sspoerri Lv 1 4 pts. 3,713
  9. Avatar for jojo2525 739. jojo2525 Lv 1 4 pts. 3,700
  10. Avatar for MinecraftMaster 740. MinecraftMaster Lv 1 4 pts. 3,700

Comments


DoctorSockrates Lv 1

I was wondering when something like this would turn up. Glad to see an unrestricted proving ground for future projects.

KALYPSO Lv 1

Soap,,,,breaks the faty around the cell ,,,hmmmmm,,,puzzle that,,,just saying,,,try it

Bautho Lv 1

I don't know what is / I did wrong, but I designed a fold - perfectly fine, but after a while I wiggled, and one part of the protein will start to unfold (the helix is not a helix anymore) and the score goes down instead of up.
I sent the structure to scientists - if you could reproduce that behavior would be interesting! :)