Placeholder image of a protein
Icon representing a puzzle

Protein Design Sandbox

Closed since about 4 years ago

Beginner

Summary

Created
March 22, 2020
Expires
Max points
100
Description

Experiment with protein design! We've disabled many of the restrictions in normal Science puzzles, so players have access to all protein designs tools, and may insert and delete any number of residues. Foldit scientists do not check the solutions from this puzzle, and playing this puzzle will not affect your global or category rankings.



Two common protein design Objectives are available, but they will not award any bonuses or penalties. The Core Existence Objective checks to see if 30% of residues are buried in the protein core, away from the water surrounding the protein. The Ideal Loops Objective looks for loops with problematic backbone folds. If you build an especially large protein, try disabling these Objectives to improve Foldit's performance.

Top groups

  1. Avatar for Anthropic Dreams
    1. Anthropic Dreams
    100 pts. 46,086
  2. Avatar for Contenders 2. Contenders 95 pts. 40,014
  3. Avatar for Gargleblasters 3. Gargleblasters 90 pts. 37,120
  4. Avatar for Beta Folders 4. Beta Folders 84 pts. 32,500
  5. Avatar for BOINC@Poland 5. BOINC@Poland 80 pts. 29,493
  6. Avatar for Team China 6. Team China 75 pts. 29,032
  7. Avatar for Go Science 7. Go Science 70 pts. 25,493
  8. Avatar for Russian team 8. Russian team 66 pts. 25,114
  9. Avatar for Australia 9. Australia 62 pts. 22,809
  10. Avatar for Penny-Arcade 10. Penny-Arcade 58 pts. 22,049
  1. Avatar for lhocare 841. lhocare Lv 1 2 pts. 2,625
  2. Avatar for Hubertjuergens 842. Hubertjuergens Lv 1 2 pts. 2,624
  3. Avatar for Peebee94 843. Peebee94 Lv 1 2 pts. 2,619
  4. Avatar for little cretan 844. little cretan Lv 1 2 pts. 2,613
  5. Avatar for MadHuman 845. MadHuman Lv 1 2 pts. 2,611
  6. Avatar for YashviP20 846. YashviP20 Lv 1 2 pts. 2,610
  7. Avatar for Funkypower 847. Funkypower Lv 1 2 pts. 2,607
  8. Avatar for Cicero Rodrigues da Silva 848. Cicero Rodrigues da Silva Lv 1 2 pts. 2,597
  9. Avatar for Narun 849. Narun Lv 1 2 pts. 2,597
  10. Avatar for ysh.titanic 850. ysh.titanic Lv 1 2 pts. 2,595

Comments

DoctorSockrates Lv 1

I was wondering when something like this would turn up. Glad to see an unrestricted proving ground for future projects.

KALYPSO Lv 1

Soap,,,,breaks the faty around the cell ,,,hmmmmm,,,puzzle that,,,just saying,,,try it

Bautho Lv 1

I don't know what is / I did wrong, but I designed a fold - perfectly fine, but after a while I wiggled, and one part of the protein will start to unfold (the helix is not a helix anymore) and the score goes down instead of up.
I sent the structure to scientists - if you could reproduce that behavior would be interesting! :)