Placeholder image of a protein
Icon representing a puzzle

1958: BAM Complex with Electron Density

Closed since about 5 years ago

Novice Overall Prediction Electron Density

Summary

Created
February 18, 2021
Expires
Max points
100
Description

This is a followup to Puzzle 1952, now starting from the structure that was originally published. This protein is part of a large protein complex with multiple subunits, which was recently solved by cryo-electron microscopy (cryo-EM) at 4.2A resolution. Unfortunately, the solved structure could really use some work so we are hoping you can improve the structure. The starting structure also includes several locked protein fragments in the electron density cloud. These are additional proteins that are also present, and are expected to make interactions with the final folded structure. Good luck!

Top groups

  1. Avatar for Anthropic Dreams
    1. Anthropic Dreams
    100 pts. 17,469
  2. Avatar for Go Science 2. Go Science 73 pts. 17,340
  3. Avatar for L'Alliance Francophone 3. L'Alliance Francophone 52 pts. 17,279
  4. Avatar for Marvin's bunch 4. Marvin's bunch 36 pts. 17,201
  5. Avatar for Beta Folders 5. Beta Folders 24 pts. 17,193
  6. Avatar for HMT heritage 6. HMT heritage 16 pts. 17,100
  7. Avatar for Contenders 7. Contenders 10 pts. 16,989
  8. Avatar for Gargleblasters 8. Gargleblasters 6 pts. 16,977
  9. Avatar for Italiani Al Lavoro 9. Italiani Al Lavoro 4 pts. 16,692
  10. Avatar for Olsztynek 10. Olsztynek 2 pts. 16,615
  1. Avatar for PieThrower 21. PieThrower Lv 1 44 pts. 17,107
  2. Avatar for O Seki To 22. O Seki To Lv 1 42 pts. 17,100
  3. Avatar for MicElephant 23. MicElephant Lv 1 40 pts. 17,069
  4. Avatar for nicobul 24. nicobul Lv 1 38 pts. 17,064
  5. Avatar for xythus 25. xythus Lv 1 37 pts. 17,062
  6. Avatar for WBarme1234 26. WBarme1234 Lv 1 35 pts. 17,059
  7. Avatar for fiendish_ghoul 27. fiendish_ghoul Lv 1 33 pts. 17,050
  8. Avatar for guineapig 28. guineapig Lv 1 32 pts. 17,018
  9. Avatar for georg137 29. georg137 Lv 1 30 pts. 16,989
  10. Avatar for Enzyme 30. Enzyme Lv 1 29 pts. 16,968

Comments

Formula350 Lv 1

This is 1958.

It'll be up to BKoep if he feels its necessary, given it's technically a minor, non-game breaking issue…. But on the other hand, IS going to be confusing at times for the next week. lol

Personally, I'm not sure I'd rank it "Novice" either, but it is certainly easier compared to the last one, since it's not a Prediction puzzle.

beta_helix Staff Lv 1

I renamed it to 1958 :-)
We'll keep it at Novice because you can still fold this puzzle without the density (so novices can still enjoy it ;-)

jeff101 Lv 1 

Are the ED cloud and locked structures the same
in both Puzzles 1952 & 1958? If we have identical
unlocked structures in 1952 & 1958, should our
scores in both puzzles be the same? If all these
things are the same, why not let us load solutions 
from 1952 into 1958? So far, 1958 has not let me 
load solutions from 1952.

beta_helix Staff Lv 1

I'm sorry that this is not possible, but fixing the bug (which caused the locked residues in 1952 to explode) has made loading in previous solutions impossible.

jeff101 Lv 1

Is scoring the same in 1952 & 1958?
Right now my score in 1958 is better
than any score I got in 1952. My best
1958 solution also looks better than
my best in 1952.