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1990: TNK1 with Density: Round 2

Closed since about 5 years ago

Novice Novice Novice Novice Novice Novice Novice Novice Novice Overall Overall Overall Overall Overall Overall Overall Overall Overall Prediction Prediction Prediction Prediction Prediction Prediction Prediction Prediction Prediction Electron Density Electron Density Electron Density Electron Density Electron Density Electron Density Electron Density Electron Density Electron Density

Summary

Created: May 06, 2021
Expires: May 13, 2021 at 18:00 UTC
Max points: 100

Description

Fold this TNK1 protein into the electron density map! This is a follow up to Puzzle 1984, now starting from the crystallographer's best model. We want to know if you can improve it!

TNK1 is a non-receptor protein tyrosine kinase NRPTK that has been implicated in the regulation of cell growth and cell death. This puzzle might be difficult, as this structure is not similar to known solved proteins. This electron density map comes from x-ray crystallography experiments, and outlines the shape of the folded protein. Help us determine the structure of this TNK1 variant by folding it in the electron density!