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Design of the Month: August 2021

Closed since over 4 years ago

Intermediate

Summary

Created
August 01, 2021
Expires
Max points
100
Description

This sandbox puzzle features a designed binder for the TGF receptor, created by an anonymous player in Puzzle 2014. The hydrophobic residues at the interface will make for tight binding. The polar residues at the binding interface satisfy buried polar atoms on the target, but they also ensure that the binder will fold even in the absence of the target. For more, check out Foldit Lab Report #23 on YouTube! This sandbox puzzle is non-competitive and will not award any points.



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