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2268: Electron Density Reconstruction 28

Closed since about 3 years ago

Novice Overall Prediction Electron Density

Summary

Created
February 21, 2023
Expires
Max points
100
Description

The structure of this protein has already been solved and published, but close inspection suggests that there are some problems with the published solution. We'd like to see if Foldit players can use the same electron density data to reconstruct a better model. There are two chains in this puzzle that have the same sequence.

Sequence
SDKLELLLDIPLKVTVELGRTRMTLKRVLEMIHGSIIELDKLTGEPVDILVNGKLIARGEVVVIDENFGVRITEIVSPKERLELLNESDKLELLLDIPLKVTVELGRTRMTLKRVLEMIHGSIIELDKLTGEPVDILVNGKLIARGEVVVIDENFGVRITEIVSPKERLELLNE

Top groups

  1. Avatar for Anthropic Dreams
    1. Anthropic Dreams
    100 pts. 28,185
  2. Avatar for Go Science 2. Go Science 71 pts. 28,184
  3. Avatar for Contenders 3. Contenders 49 pts. 28,117
  4. Avatar for FamilyBarmettler 4. FamilyBarmettler 33 pts. 27,967
  5. Avatar for L'Alliance Francophone 5. L'Alliance Francophone 22 pts. 27,966
  6. Avatar for Void Crushers 6. Void Crushers 14 pts. 27,949
  7. Avatar for Marvin's bunch 7. Marvin's bunch 8 pts. 27,817
  8. Avatar for OmHS 8. OmHS 5 pts. 27,604
  9. Avatar for VeFold 9. VeFold 2 pts. 27,482
  10. Avatar for AlphaFold 10. AlphaFold 3 pts. 27,482
  1. Avatar for gmn 21. gmn Lv 1 25 pts. 27,832
  2. Avatar for fpc 22. fpc Lv 1 23 pts. 27,817
  3. Avatar for equilibria 23. equilibria Lv 1 21 pts. 27,746
  4. Avatar for bamh 24. bamh Lv 1 20 pts. 27,744
  5. Avatar for georg137 25. georg137 Lv 1 18 pts. 27,727
  6. Avatar for hansvandenhof 26. hansvandenhof Lv 1 17 pts. 27,715
  7. Avatar for alcor29 27. alcor29 Lv 1 15 pts. 27,682
  8. Avatar for PieThrower 28. PieThrower Lv 1 14 pts. 27,654
  9. Avatar for Kayceecyr65 29. Kayceecyr65 Lv 1 13 pts. 27,604
  10. Avatar for Idiotboy 30. Idiotboy Lv 1 12 pts. 27,576

Comments

LociOiling Lv 1

Looks like two chains this time:

sdklellldiplkvtvelgrtrmtlkrvlemihgsiieldkltgepvdilvngkliargevvvidenfgvriteivspkerlell    (1 -  85)
sdklellldiplkvtvelgrtrmtlkrvlemihgsiieldkltgepvdilvngkliargevvvidenfgvriteivspkerlellne (86 - 172)

Once again AA Edit and other recipes fail to detect the chains, but soon….

grogar7 Lv 1

So both the puzzle description and the sequence quoted in the description are incorrect. The chains are not identical. Chain #1 is lacking the 'ne' end. So chain #1 is 85 residues and chain #2 is 87 residues.