2388: Electron Density Reconstruction 68

Closed since over 2 years ago

Summary

• Created: November 29, 2023
• Expires: December 14, 2023 at 18:00 UTC
• Max points: 100

Description

The structure of this protein has already been solved and published, but close inspection suggests that there are some problems with the published solution. We'd like to see if Foldit players can use the same electron density data to reconstruct a better model. This one is considerably smaller than the last puzzle!

• Sequence: MGSSHHHHHHSSGLVPRGSHMRVPLDEIDKKIIKILQNDGKAPLREISKITGLAESTIHERIRKLRESGVIKKFTAIIDPEALGYSMLAFILVKVKAGKYSEVASNLAKYPEIVEVYETTGDYDMVVKIRTKNSEELNNFLDLIGSIPGVEGTHTMIVLKTHKETTELPIK

Top groups

• 1. Anthropic Dreams 100 pts. 24,794
• 2. L'Alliance Francophone 63 pts. 24,743
• 3. Go Science 37 pts. 24,734
• 4. Contenders 21 pts. 24,696
• 5. Marvin's bunch 11 pts. 24,681
• 6. Gargleblasters 5 pts. 24,616
• 7. FamilyBarmettler 2 pts. 24,540
• 8. Australia 1 pt. 24,494
• 9. BOINC@Poland 1 pt. 24,251
• 10. VeFold 1 pt. 24,177

Top evolvers

• 1. LociOiling 100 pts. 24,789
• 2. Galaxie 41 pts. 24,783
• 3. alcor29 14 pts. 24,743
• 4. Sandrix72 4 pts. 24,734
• 5. Bruno Kestemont 1 pt. 24,727
• 6. silent gene 1 pt. 24,594
• 7. ProteinGujo 1 pt. 23,367

Comments

[Artoria2e5]

Hard to tell which PDB it is, because people seem to really like looking at this lad: https://www.ncbi.nlm.nih.gov/ipg/1RI7_A. Well, probably 1RI7.

PDB-REDO says 3 peptides flipped. Indeed, some parts of the structure get vastly improved with remixing! I don't think they were same residues (PDB# 26, 56) though…