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2424: Electron Density Reconstruction 80

Closed since about 2 years ago

Novice Overall Prediction Electron Density

Summary


Created
February 22, 2024
Expires
Max points
100
Description

The structure of this protein has already been solved and published, but close inspection suggests that there are some problems with the published solution. We'd like to see if Foldit players can use the same electron density data to reconstruct a better model. There's two copies of two chains each in this structure, two of which are quite short.

Sequence
A, C: MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKAF. B,D: FRSKGEELFT

Top groups


  1. Avatar for Kotocycle 11. Kotocycle 1 pt. 34,920
  2. Avatar for BOINC@Poland 12. BOINC@Poland 1 pt. 34,740
  3. Avatar for BIOTF345 13. BIOTF345 1 pt. 29,766
  4. Avatar for SHELL 14. SHELL 1 pt. 29,061
  5. Avatar for BIOF215 15. BIOF215 1 pt. 28,324
  6. Avatar for AlphaFold 16. AlphaFold 1 pt. 21,059
  7. Avatar for BioInformatics2024 17. BioInformatics2024 1 pt. 19,640

  1. Avatar for christioanchauvin 100 pts. 36,040
  2. Avatar for LociOiling 2. LociOiling Lv 1 96 pts. 36,010
  3. Avatar for Sandrix72 3. Sandrix72 Lv 1 92 pts. 36,010
  4. Avatar for Punzi Baker 3 4. Punzi Baker 3 Lv 1 89 pts. 36,001
  5. Avatar for Galaxie 5. Galaxie Lv 1 85 pts. 35,954
  6. Avatar for dcrwheeler 6. dcrwheeler Lv 1 81 pts. 35,932
  7. Avatar for Bletchley Park 7. Bletchley Park Lv 1 78 pts. 35,932
  8. Avatar for MicElephant 8. MicElephant Lv 1 75 pts. 35,924
  9. Avatar for BackBuffer 9. BackBuffer Lv 1 71 pts. 35,923
  10. Avatar for gmn 10. gmn Lv 1 68 pts. 35,917

Comments


Serca Lv 1

Secondary structure prediction (JPred) is pretty close to what we see here.
LLLLLLLLLEEEEEELLLLLLHHHHHHHHHHHLLLLHHHHHHHHHHHHLLLLEEEEEELHHHHHHHHHHHHHHHHHLLLLLEEEEELLLLLLLLLLLLLLLLLLLLLHHHHHHHHLLLLLLLEEEEEELLLLLLHHHHHHHHHHHLLLLHHHHHHHHHHHHLLLLEEEEEELHHHHHHHHHHHHHHHHHLLLLLEEEEELLLLLLLL