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2424: Electron Density Reconstruction 80

Closed since about 2 years ago

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Summary

Created
February 22, 2024
Expires
Max points
100
Description

The structure of this protein has already been solved and published, but close inspection suggests that there are some problems with the published solution. We'd like to see if Foldit players can use the same electron density data to reconstruct a better model. There's two copies of two chains each in this structure, two of which are quite short.

Sequence
A, C: MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKAF. B,D: FRSKGEELFT

Top groups

  1. Avatar for L'Alliance Francophone
    1. L'Alliance Francophone
    100 pts. 36,040
  2. Avatar for Anthropic Dreams 2. Anthropic Dreams 73 pts. 36,010
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  1. Avatar for U202342272 111. U202342272 Lv 1 1 pt. 19,665
  2. Avatar for cheetoman2025 112. cheetoman2025 Lv 1 1 pt. 19,640
  3. Avatar for dhruv_pai_angle 113. dhruv_pai_angle Lv 1 1 pt. 19,640
  4. Avatar for nkhamnei 114. nkhamnei Lv 1 1 pt. 19,640
  5. Avatar for yvonnnnne 115. yvonnnnne Lv 1 1 pt. 19,640
  6. Avatar for shashwat1807 116. shashwat1807 Lv 1 1 pt. 19,640
  7. Avatar for AdityaV 117. AdityaV Lv 1 1 pt. 19,640
  8. Avatar for Entropy 118. Entropy Lv 1 1 pt. 19,640
  9. Avatar for Arlind1 119. Arlind1 Lv 1 1 pt. 19,640
  10. Avatar for Salmon_Ella 120. Salmon_Ella Lv 1 1 pt. 19,640

Comments

Serca Lv 1

Secondary structure prediction (JPred) is pretty close to what we see here.
LLLLLLLLLEEEEEELLLLLLHHHHHHHHHHHLLLLHHHHHHHHHHHHLLLLEEEEEELHHHHHHHHHHHHHHHHHLLLLLEEEEELLLLLLLLLLLLLLLLLLLLLHHHHHHHHLLLLLLLEEEEEELLLLLLHHHHHHHHHHHLLLLHHHHHHHHHHHHLLLLEEEEEELHHHHHHHHHHHHHHHHHLLLLLEEEEELLLLLLLL