Icon representing a puzzle

Beginner Puzzle: Coronavirus

Closed since over 1 year ago

Beginner

Summary

Created
September 26, 2024
Expires
Max points
100
Description

Design a protein binder against coronavirus! The starting structure shows how the coronavirus spike protein binds to a human receptor protein. The coronavirus protein (in gray) is mostly frozen, except for the orange and blue sidechains at the binding site. The binding site of coronavirus sticks to the human protein (in color), and this allows the coronavirus to infect human cells. We want to design a new protein that can bind to coronavirus more tightly than the human protein! A tight binder could block the normal coronavirus-human interaction, and might be used as an antiviral drug against coronavirus! Refold and mutate the starting structure to increase your score and improve binding against coronavirus! This is a Beginner puzzle for new players that have joined Foldit in the last 6 months.

Top groups

  1. Avatar for Rechenkraft.net 11. Rechenkraft.net 1 pt. 11,894
  2. Avatar for UPJ Biochem 25 12. UPJ Biochem 25 1 pt. 11,753
  3. Avatar for ORIS 13. ORIS 1 pt. 11,753
  1. Avatar for Anthonyk07 271. Anthonyk07 Lv 1 4 pts. 11,753
  2. Avatar for DonM03 272. DonM03 Lv 1 4 pts. 11,753
  3. Avatar for Charlotte Stewart 273. Charlotte Stewart Lv 1 4 pts. 11,753
  4. Avatar for lizzyyy 274. lizzyyy Lv 1 4 pts. 11,753
  5. Avatar for sofiejaa 275. sofiejaa Lv 1 3 pts. 11,753
  6. Avatar for gonpa24 276. gonpa24 Lv 1 3 pts. 11,753
  7. Avatar for kilbr24 277. kilbr24 Lv 1 3 pts. 11,753
  8. Avatar for kkkkkkkkkkkkkkkkkkkk 278. kkkkkkkkkkkkkkkkkkkk Lv 1 3 pts. 11,753
  9. Avatar for casli24 279. casli24 Lv 1 3 pts. 11,753
  10. Avatar for ojonesthomas 280. ojonesthomas Lv 1 3 pts. 11,753

Comments