Placeholder image of a protein
Icon representing a puzzle

2604: Electron Density Reconstruction 116

Closed since 10 months ago

Novice Overall Prediction Electron Density

Summary

Created
April 23, 2025
Expires
Max points
100
Description

The structure of this protein has already been solved and published, but close inspection suggests that there are some problems with the published solution. We'd like to see if Foldit players can use the same electron density data to reconstruct a better model. This puzzle is fairly large with two copies of the protein, so we highly recommend using the Trim tool.

Sequence
TVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSSAWSHPQFEK

Top groups

  1. Avatar for Go Science
    1. Go Science
    100 pts. 61,469
  2. Avatar for Anthropic Dreams 2. Anthropic Dreams 60 pts. 61,083
  3. Avatar for Contenders 3. Contenders 33 pts. 60,706
  4. Avatar for L'Alliance Francophone 4. L'Alliance Francophone 17 pts. 59,748
  5. Avatar for Australia 5. Australia 8 pts. 59,359
  6. Avatar for Void Crushers 6. Void Crushers 4 pts. 59,338
  7. Avatar for Gargleblasters 7. Gargleblasters 2 pts. 58,907
  8. Avatar for FamilyBarmettler 8. FamilyBarmettler 1 pt. 58,802
  9. Avatar for VeFold 9. VeFold 1 pt. 57,488
  10. Avatar for Marvin's bunch 10. Marvin's bunch 1 pt. 57,036
  1. Avatar for pizpot 61. pizpot Lv 1 1 pt. 50,709
  2. Avatar for Dagahn 62. Dagahn Lv 1 1 pt. 50,177
  3. Avatar for furi0us 63. furi0us Lv 1 1 pt. 50,127
  4. Avatar for efull 64. efull Lv 1 1 pt. 49,856
  5. Avatar for Fasodankfds 65. Fasodankfds Lv 1 1 pt. 48,540
  6. Avatar for Anvani_09118 66. Anvani_09118 Lv 1 1 pt. 46,518
  7. Avatar for rosie4loop 67. rosie4loop Lv 1 1 pt. 45,903
  8. Avatar for apetrides 68. apetrides Lv 1 1 pt. 43,827
  9. Avatar for Granola Dave 69. Granola Dave Lv 1 1 pt. 43,418
  10. Avatar for Osiris 70. Osiris Lv 1 1 pt. 30,394

Comments

LociOiling Lv 1

This week's puzzle is a match for PDB 2Y4P, among others.

It's cheerfully described as a "DEATH-ASSOCIATED PROTEIN KINASE" in some entries, or just "DAP" in others.

Puzzle: 2604: Electron Density Reconstruction 116
segment count = 552
2 chains and ligands
chain A (protein), segments 1-276, length = 276
tvfrqenvddyydtgeelgsgqfavvkkcrekstglqyaakfikkrrtkssrrgvsredierevsilkeiqhpnvitlhevyenktdvililelvaggelfdflaekeslteeeateflkqilngvyylhslqiahfdlkpenimlldrnvpkprikiidfglahkidfgnefknifgtpefvapeivnyeplgleadmwsigvityillsgaspflgdtkqetlanvsavnyefedeyfsntsalakdfirrllvkdpkkrmtiqdslqhpwikp
chain B (protein), segments 277-552, length = 276
tvfrqenvddyydtgeelgsgqfavvkkcrekstglqyaakfikkrrtkssrrgvsredierevsilkeiqhpnvitlhevyenktdvililelvaggelfdflaekeslteeeateflkqilngvyylhslqiahfdlkpenimlldrnvpkprikiidfglahkidfgnefknifgtpefvapeivnyeplgleadmwsigvityillsgaspflgdtkqetlanvsavnyefedeyfsntsalakdfirrllvkdpkkrmtiqdslqhpwikp

(edit: provided better PDB link)