Icon representing a puzzle

2632: Revisiting Puzzle 140: Rosetta Decoy 4

Closed since 8 months ago

Novice Overall Prediction

Summary

Created
July 09, 2025
Expires
Max points
100
Description

This is a throwback puzzle to the early days of Foldit. This protein helps to regulate oxidation in the cell; the starting structure is a model produced by Rosetta. This protein contains four cysteine residues, but in this state only two of them are expected to oxidize to form a single disulfide bond. We are revisiting old Foldit puzzles so we can see how useful the recent additions to the game have been and to provide newer players with puzzles that are still scientifically relevant.

Sequence
MPVNQIQETISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQCYL

Top groups

  1. Avatar for Anthropic Dreams
    1. Anthropic Dreams
    100 pts. 11,749
  2. Avatar for Go Science 2. Go Science 70 pts. 11,554
  3. Avatar for Contenders 3. Contenders 47 pts. 11,434
  4. Avatar for L'Alliance Francophone 4. L'Alliance Francophone 30 pts. 11,379
  5. Avatar for VeFold 5. VeFold 19 pts. 11,290
  6. Avatar for Void Crushers 6. Void Crushers 11 pts. 11,283
  7. Avatar for Australia 7. Australia 7 pts. 11,261
  8. Avatar for Marvin's bunch 8. Marvin's bunch 4 pts. 11,246
  9. Avatar for FamilyBarmettler 9. FamilyBarmettler 2 pts. 11,098
  10. Avatar for Bioqué? 10. Bioqué? 1 pt. 10,418
  1. Avatar for LociOiling
    1. LociOiling Lv 1
    100 pts. 11,748
  2. Avatar for Galaxie 2. Galaxie Lv 1 52 pts. 11,740
  3. Avatar for gmn 3. gmn Lv 1 24 pts. 11,721
  4. Avatar for alcor29 4. alcor29 Lv 1 10 pts. 11,707
  5. Avatar for Bruno Kestemont 5. Bruno Kestemont Lv 1 4 pts. 11,547
  6. Avatar for toshiue 6. toshiue Lv 1 1 pt. 11,514
  7. Avatar for Anfinsen_slept_here 7. Anfinsen_slept_here Lv 1 1 pt. 11,490
  8. Avatar for georg137 8. georg137 Lv 1 1 pt. 11,315
  9. Avatar for Bletchley Park 9. Bletchley Park Lv 1 1 pt. 11,308

Comments