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2666: Electron Density Reconstruction 137

Closed since 5 months ago

Novice Overall Prediction Electron Density

Summary

Created
September 17, 2025
Expires
Max points
100
Description

The structure of this protein has already been solved and published, but close inspection suggests that there are some problems with the published solution. We'd like to see if Foldit players can use the same electron density data to reconstruct a better model.

Sequence
MEYEITNYSERHTELPGHFIGLNTVDKLEESPLRDFVKSHGGHTVISKILIANNGIAAVKEIRSVRKWAYETFGDDRTVQFVAMATPEDLEANAEYIRMADQYIEVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLPEKLSQSKRKVIFIGPPGNAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTGLVSVDDDIYQKGCCTSPEDGLQKAKRIGFPVMIKASEGGGGKGIRQVEREEDFIALYHQAANEIPGSPIFIMKLAGRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPVTIAKAETFHEMEKAAVRLGKLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGIPMHRISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIPKGHCTACRITSEDPNDGFKPSGGTLHELNFRSSSNVWGYFSVGNNGNIHSFSDSQFGHIFAFGENRQASRKHMVVALKELSIRGDFRTTVEYLIKLLETEDFEDNTITTGWLDDLI

Top groups

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  1. Avatar for bravosk8erboy
    1. bravosk8erboy Lv 1
    100 pts. 66,332
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  3. Avatar for ichwilldiesennamen 3. ichwilldiesennamen Lv 1 87 pts. 66,017
  4. Avatar for spvincent 4. spvincent Lv 1 81 pts. 65,944
  5. Avatar for Bruno Kestemont 5. Bruno Kestemont Lv 1 75 pts. 65,793
  6. Avatar for nicobul 6. nicobul Lv 1 69 pts. 65,723
  7. Avatar for Bletchley Park 7. Bletchley Park Lv 1 64 pts. 65,715
  8. Avatar for Dr. Goochie 8. Dr. Goochie Lv 1 59 pts. 65,708
  9. Avatar for LociOiling 9. LociOiling Lv 1 55 pts. 65,705
  10. Avatar for christioanchauvin 10. christioanchauvin Lv 1 50 pts. 65,608

Comments

LociOiling Lv 1

Still pre-release, but based on the sequence above, this one matches PDB 1W93 and 1W96, among others. We'll have to wait for the puzzle to see what the best match is.

LociOiling Lv 1

Upon close inspection, PDB 1W93 is an exact match. The key is missing residues DFRT, splitting the puzzle into two chains as far as AA Edit is concerned.