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2666: Electron Density Reconstruction 137

Closed since 5 months ago

Novice Overall Prediction Electron Density

Summary

Created
September 17, 2025
Expires
Max points
100
Description

The structure of this protein has already been solved and published, but close inspection suggests that there are some problems with the published solution. We'd like to see if Foldit players can use the same electron density data to reconstruct a better model.

Sequence
MEYEITNYSERHTELPGHFIGLNTVDKLEESPLRDFVKSHGGHTVISKILIANNGIAAVKEIRSVRKWAYETFGDDRTVQFVAMATPEDLEANAEYIRMADQYIEVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLPEKLSQSKRKVIFIGPPGNAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTGLVSVDDDIYQKGCCTSPEDGLQKAKRIGFPVMIKASEGGGGKGIRQVEREEDFIALYHQAANEIPGSPIFIMKLAGRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPVTIAKAETFHEMEKAAVRLGKLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGIPMHRISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIPKGHCTACRITSEDPNDGFKPSGGTLHELNFRSSSNVWGYFSVGNNGNIHSFSDSQFGHIFAFGENRQASRKHMVVALKELSIRGDFRTTVEYLIKLLETEDFEDNTITTGWLDDLI

Top groups

  1. Avatar for Contenders
    1. Contenders
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  2. Avatar for Go Science 2. Go Science 73 pts. 66,350
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  1. Avatar for Bletchley Park
    1. Bletchley Park Lv 1
    100 pts. 66,581
  2. Avatar for Bruno Kestemont 2. Bruno Kestemont Lv 1 33 pts. 66,350
  3. Avatar for Galaxie 3. Galaxie Lv 1 8 pts. 66,138
  4. Avatar for bravosk8erboy 4. bravosk8erboy Lv 1 2 pts. 66,117
  5. Avatar for LociOiling 5. LociOiling Lv 1 1 pt. 66,089
  6. Avatar for Anfinsen_slept_here 6. Anfinsen_slept_here Lv 1 1 pt. 65,323

Comments

LociOiling Lv 1

Still pre-release, but based on the sequence above, this one matches PDB 1W93 and 1W96, among others. We'll have to wait for the puzzle to see what the best match is.

LociOiling Lv 1

Upon close inspection, PDB 1W93 is an exact match. The key is missing residues DFRT, splitting the puzzle into two chains as far as AA Edit is concerned.