Placeholder image of a protein
Icon representing a puzzle

2666: Electron Density Reconstruction 137

Closed since 5 months ago

Novice Overall Prediction Electron Density

Summary

Created
September 17, 2025
Expires
Max points
100
Description

The structure of this protein has already been solved and published, but close inspection suggests that there are some problems with the published solution. We'd like to see if Foldit players can use the same electron density data to reconstruct a better model.

Sequence
MEYEITNYSERHTELPGHFIGLNTVDKLEESPLRDFVKSHGGHTVISKILIANNGIAAVKEIRSVRKWAYETFGDDRTVQFVAMATPEDLEANAEYIRMADQYIEVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLPEKLSQSKRKVIFIGPPGNAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTGLVSVDDDIYQKGCCTSPEDGLQKAKRIGFPVMIKASEGGGGKGIRQVEREEDFIALYHQAANEIPGSPIFIMKLAGRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPVTIAKAETFHEMEKAAVRLGKLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGIPMHRISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIPKGHCTACRITSEDPNDGFKPSGGTLHELNFRSSSNVWGYFSVGNNGNIHSFSDSQFGHIFAFGENRQASRKHMVVALKELSIRGDFRTTVEYLIKLLETEDFEDNTITTGWLDDLI

Top groups

  1. Avatar for Contenders
    1. Contenders
    100 pts. 66,581
  2. Avatar for Go Science 2. Go Science 73 pts. 66,350
  3. Avatar for Anthropic Dreams 3. Anthropic Dreams 52 pts. 66,138
  4. Avatar for L'Alliance Francophone 4. L'Alliance Francophone 36 pts. 65,723
  5. Avatar for FamilyBarmettler 5. FamilyBarmettler 24 pts. 65,417
  6. Avatar for Australia 6. Australia 16 pts. 65,055
  7. Avatar for Team China 7. Team China 10 pts. 65,007
  8. Avatar for Void Crushers 8. Void Crushers 6 pts. 64,479
  9. Avatar for Marvin's bunch 9. Marvin's bunch 4 pts. 64,404
  10. Avatar for VeFold 10. VeFold 2 pts. 63,957
  1. Avatar for Xendrais 21. Xendrais Lv 1 19 pts. 64,840
  2. Avatar for georg137 22. georg137 Lv 1 17 pts. 64,697
  3. Avatar for akaaka 23. akaaka Lv 1 15 pts. 64,694
  4. Avatar for TheGUmmer 24. TheGUmmer Lv 1 14 pts. 64,479
  5. Avatar for jausmh 25. jausmh Lv 1 12 pts. 64,404
  6. Avatar for NinjaGreg 26. NinjaGreg Lv 1 11 pts. 64,316
  7. Avatar for Anfinsen_slept_here 27. Anfinsen_slept_here Lv 1 10 pts. 64,279
  8. Avatar for Dr.Sillem 28. Dr.Sillem Lv 1 9 pts. 63,957
  9. Avatar for Idiotboy 29. Idiotboy Lv 1 8 pts. 63,957
  10. Avatar for zxspectrum 30. zxspectrum Lv 1 7 pts. 63,882

Comments

LociOiling Lv 1

Still pre-release, but based on the sequence above, this one matches PDB 1W93 and 1W96, among others. We'll have to wait for the puzzle to see what the best match is.

LociOiling Lv 1

Upon close inspection, PDB 1W93 is an exact match. The key is missing residues DFRT, splitting the puzzle into two chains as far as AA Edit is concerned.