Icon representing a puzzle

Beginner Puzzle: Docking Design

Closed since about 2 months ago

Beginner

Summary


Created
December 11, 2025
Expires
Max points
100
Description

We are giving you a helix positioned over a hydrophobic groove where binding occurs in nature. You can mutate any residue on the helix but none on the native binding region. Try to look for favorable hydrophobic interactions in this groove while maintaining the helix. For new players that have joined Foldit in the last 6 months.

Top groups


  1. Avatar for CBE_ProEn_2025 100 pts. 9,333
  2. Avatar for Coastal Biochemistry 2. Coastal Biochemistry 1 pt. 8,351

  1. Avatar for Rynaldos 21. Rynaldos Lv 1 5 pts. 9,102
  2. Avatar for KTZui 22. KTZui Lv 1 4 pts. 9,071
  3. Avatar for sneakypenguin 23. sneakypenguin Lv 1 3 pts. 9,025
  4. Avatar for kwokchunhim 24. kwokchunhim Lv 1 3 pts. 8,886
  5. Avatar for not_kevin 25. not_kevin Lv 1 2 pts. 8,853
  6. Avatar for teemarie 26. teemarie Lv 1 2 pts. 8,819
  7. Avatar for rainyday8078324 27. rainyday8078324 Lv 1 1 pt. 8,812
  8. Avatar for Kaibe 28. Kaibe Lv 1 1 pt. 8,620
  9. Avatar for Dr.Mk Krisz 29. Dr.Mk Krisz Lv 1 1 pt. 8,458
  10. Avatar for Kei_sui 30. Kei_sui Lv 1 1 pt. 8,388

Comments